Anaemia and malaria
NJ White - Malaria journal, 2018 - Springer
Malaria is a major cause of anaemia in tropical areas. Malaria infection causes haemolysis
of infected and uninfected erythrocytes and bone marrow dyserythropoiesis which …
of infected and uninfected erythrocytes and bone marrow dyserythropoiesis which …
Cell-free protein synthesis: applications come of age
Cell-free protein synthesis has emerged as a powerful technology platform to help satisfy the
growing demand for simple and efficient protein production. While used for decades as a …
growing demand for simple and efficient protein production. While used for decades as a …
Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Cell‐free protein synthesis: pros and cons of prokaryotic and eukaryotic systems
A Zemella, L Thoring, C Hoffmeister, S Kubick - ChemBioChem, 2015 - Wiley Online Library
From its start as a small‐scale in vitro system to study fundamental translation processes,
cell‐free protein synthesis quickly rose to become a potent platform for the high‐yield …
cell‐free protein synthesis quickly rose to become a potent platform for the high‐yield …
Exploring the potential of cell-free protein synthesis for extending the abilities of biological systems
Cell-free protein synthesis (CFPS) system is a simple, rapid, and sensitive tool that is devoid
of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and …
of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and …
Cell-free synthetic biology: engineering beyond the cell
Cell-free protein synthesis (CFPS) technologies have enabled inexpensive and rapid
recombinant protein expression. Numerous highly active CFPS platforms are now available …
recombinant protein expression. Numerous highly active CFPS platforms are now available …
Advances and challenges in malaria vaccine development
PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …
among children and pregnant women in Africa. An effective malaria vaccine would be a …
Cell-free protein synthesis: a promising option for future drug development
SK Dondapati, M Stech, A Zemella, S Kubick - BioDrugs, 2020 - Springer
Proteins are the main source of drug targets and some of them possess therapeutic potential
themselves. Among them, membrane proteins constitute approximately 50% of the major …
themselves. Among them, membrane proteins constitute approximately 50% of the major …
Development and validation of serological markers for detecting recent Plasmodium vivax infection
RJ Longley, MT White, E Takashima, J Brewster… - Nature medicine, 2020 - nature.com
A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals
carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This …
carrying clinically silent and undetectable liver-stage parasites, called hypnozoites. This …
New antigens for a multicomponent blood-stage malaria vaccine
An effective blood-stage vaccine against Plasmodium falciparum remains a research
priority, but the number of antigens that have been translated into multicomponent vaccines …
priority, but the number of antigens that have been translated into multicomponent vaccines …