Medicinal plants are essential for improving human health, and around 75% of the
population in developing countries relies mainly on herb-based medicines for health care …

Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that
has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its …

One of the aims of plant in vitro culture is to produce secondary plant metabolites using plant
cells and organ cultures, such as cell suspensions, adventitious, and hairy roots (among …

Hairy root (HR) culture, a successful biotechnology combining in vitro tissue culture with
recombinant DNA machinery, is intended for the genetic improvement of plants. This …

Ginsenosides represent the major bioactive components of ginseng. These triterpenoid
saponins have been shown to exert numerous beneficial effects on the human body. Recent …

Agrobacterium rhizogenes is a natural plant genetic engineer. It is a gram-negative soil
bacterium that induces hairy root formation. Success has been obtained in exploring the …

Paclitaxel (PTX) and its derivatives are diterpene alkaloids widely used as
chemotherapeutic agents in the treatment of various types of cancer. Due to the scarcity of …

We tested the effect of the presence in the culture medium of chitosan, vanadyl sulfate or
methyl jasmonate on growth and ginsenoside production of three stable hairy root lines of …

Hairy roots (HRs) are differentiated cultures of transformed roots generated by the infection
of wounded higher plants with Agrobacterium rhizogenes. This pathogen causes the HR …

We tested the effect of three variables: the bioreactor system (Wave or Spray reactor),
medium exchange and culture period, on the capacity of a selected hairy root line of Panax …