Vitamin effects on the immune system: vitamins A and D take centre stage

JR Mora, M Iwata, UH Von Andrian - Nature reviews immunology, 2008 - nature.com
Vitamins are essential constituents of our diet that have long been known to influence the
immune system. Vitamins A and D have received particular attention in recent years as …

Th17 cells in immunity and autoimmunity

SK Bedoya, B Lam, K Lau… - Journal of Immunology …, 2013 - Wiley Online Library
Th17 and IL‐17 play important roles in the clearance of extracellular bacterial and fungal
infections. However, strong evidence also implicates the Th17 lineage in several …

Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

KM Elias, A Laurence, TS Davidson… - Blood, The Journal …, 2008 - ashpublications.org
Abstract CD4+ helper T (Th) cells play a crucial role in the delicate balance between host
defense and autoimmune disease. Two important populations of helper T cells are the …

Retinol levels are associated with magnetic resonance imaging outcomes in multiple sclerosis

KI Løken-Amsrud, KM Myhr, SJ Bakke… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Vitamin A has immunomodulatory properties and may regulate the
transcription of genes involved in remyelination. Objective: To investigate the association …

A unique thymus-derived regulatory T cell subset associated with systemic lupus erythematosus

H Hanaoka, T Nishimoto, Y Okazaki, T Takeuchi… - Arthritis Research & …, 2020 - Springer
Background Foxp3 is a marker for regulatory T cells (Treg cells), but recent studies have
shown the plasticity and heterogeneity of CD4+ Foxp3+ T cells. This study aimed to examine …

[HTML][HTML] Effects of periodontitis on aortic insulin resistance in an obese rat model

D Ekuni, T Tomofuji, K Irie, K Kasuyama… - Laboratory …, 2010 - Elsevier
The combination of obesity and its associated risk factors, such as insulin resistance and
inflammation, results in the development of atherosclerosis. However, the effects of …

Targeting Potassium Channels Kv1.3 and KCa3.1: Routes to Selective Immunomodulators in Autoimmune Disorder Treatment?

J Wang, M Xiang - … : The Journal of Human Pharmacology and …, 2013 - Wiley Online Library
The Kv1. 3 and KC a3. 1 potassium channels are promising targets for the treatment of
autoimmune disorders. Many K v1. 3 and KC a3. 1 blockers have a more favorable adverse …

All-trans retinoic acid regulates the expression of apolipoprotein E in rats with glomerulosclerosis induced by Adriamycin

TB Zhou, YH Qin, FY Lei, LN Su, YJ Zhao… - … and molecular pathology, 2011 - Elsevier
Apolipoprotein E (apoE) is an important plasma protein in cholesterol homeostasis and
plays a key role in the progression of glomerulosclerosis (GS). We conducted this …

Retinoids differentially regulate the progression of autoimmune diabetes in three preclinical models in mice

S Stošić-Grujičić, T Cvjetićanin, I Stojanović - Molecular Immunology, 2009 - Elsevier
Retinoids have a variety of biological activities, including immunomodulatory action in a
number of inflammatory and autoimmune conditions. Considering the pathogenesis of type …

Off the beaten renin–angiotensin–aldosterone system pathway: New perspectives on antiproteinuric therapy

J Gordon, JB Kopp - Advances in chronic kidney disease, 2011 - Elsevier
CKD is a major public health problem in the developed and the developing world. The
degree of proteinuria associated with renal failure is a generally well accepted marker of …