The delivery of proteins into cells is a potential game changer for a wide array of therapeutic
purposes, including cancer therapy, immunomodulation and treatment of inherited diseases …

Gold nanoparticles (AuNPs) of different size and shape are widely used as photosensitizers
for cancer diagnostics and plasmonic photothermal (PPT)/photodynamic (PDT) therapy, as …

Nanoparticle-sensitized photoporation is an upcoming approach for the intracellular delivery
of biologics, combining high efficiency and throughput with excellent cell viability. However …

Laser-assisted photoporation is a promising technique that is receiving increasing attention
for the delivery of membrane impermeable nanoscopic substances into living cells …

Genetically modified animals are state of the art in biomedical research as gene therapy is a
promising perspective in the attempt to cure hereditary diseases. Both approaches have in …

Exploiting bacterial DNA-acting enzymes and expanding their repertoire for genome
engineering have been major technological and conceptual advances in molecular biology …

Engineering the spatial organisation of organotypic cultures is pivotal for refining tissue
models that are useful for gaining deeper insights into complex, non‐cell autonomous …

T lymphocytes are the major drivers of antitumor immunity. The recent clinical success of
adoptive T cell therapies and immune checkpoint inhibitors has demonstrated the strength of …

Current cancer therapies are frequently ineffective and associated with severe side effects
and with acquired cancer drug resistance. The development of effective therapies has been …

Cell membrane composed of lipid bilayer is a selectively permeable membrane that only
allows specific molecules to pass through. While such selectivity is essential for the survival …