Hyperglycemia and insulin resistance are key players in the development of atherosclerosis
and its complications. A large body of evidence suggest that metabolic abnormalities cause …

In healthy individuals, the vascular endothelium regulates an intricate balance of factors that
maintain vascular homeostasis and normal arterial function. Functional disruption of the …

Aims Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide
and results from an obstruction in the blood supply to a region of the heart. In an attempt to …

Diabetes is the most common metabolic disorder and is recognized as one of the most
important health threats of our time. MicroRNAs (miRNAs) are a novel group of non-coding …

A cluster of miR‐221/222 is a key player in vascular biology through exhibiting its effects on
vascular smooth muscle cells (VSMCs) and endothelial cells (ECs). These miRNAs …

Empagliflozin (EMPA), a drug approved for type 2 diabetes management, reduced
cardiovascular death but is unknown if it reduces myocardial infarction. We sought to …

This study aimed to evaluate the effect of mesenchymal stem cells (MSCs)–derived
exosomes in retina regeneration of experimentally induced diabetes mellitus (DM) in a …

Background Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development
of Diabetic nephropathy (DN) leading to End Stage Renal Disease. Hence a better …

Endothelial microparticles (EMP) are released from activated or apoptotic endothelial cells
(EC s) and can be taken up by adjacent EC s, but their effect on vascular inflammation after …

The incidence of diabetes is escalating worldwide and, consequently, this has become a
major health care problem. Moreover, both type 1 and type 2 diabetes are associated with …