Neurobiological mechanisms in the kynurenine pathway and major depressive disorder
AG Bertollo, MED Mingoti, ZM Ignácio - Reviews in the …, 2024 - degruyter.com
Major depressive disorder (MDD) is a prevalent psychiatric disorder that has damage to
people's quality of life. Tryptophan is the precursor to serotonin, a critical neurotransmitter in …
people's quality of life. Tryptophan is the precursor to serotonin, a critical neurotransmitter in …
Synthesis, Characterization and DFT Study of 4, 4′-Oxydianiline Imines as Precursors of Tetrahalo-1, 3-oxazepine-1, 5-dione
AH Kshash, MG Mokhlef - Indonesian Journal of Chemistry, 2017 - journal.ugm.ac.id
This work presents four Schiff bases derived from 4, 4′-Oxydianiline, distinguished by the
para substituted halogen of benzaldehyde. These bases were used to synthesize eight …
para substituted halogen of benzaldehyde. These bases were used to synthesize eight …
Preparation and Identification of Novel 1, 3-Oxazepine Derivatives by Cycloaddition Reactions [2+ 5] of Selected Carboxylic Acid Anhydrides with Imines Derived from …
OH Abid - Al-Mustansiriyah Journal of Science, 2018 - mjs.uomustansiriyah.edu.iq
Novel 1, 3-oxazepine derivatives have been synthesis via (2+ 5) cycloaddition reaction of
imines and selected cyclic carboxylic acid anhydrides by refluxing in dry benzene. Imines …
imines and selected cyclic carboxylic acid anhydrides by refluxing in dry benzene. Imines …
High-throughput screening against 6.1 million structurally diverse, lead-like compounds to discover novel ROCK inhibitors for cerebral injury recovery
H Gong, Z Yuan, L Zhan - Molecular diversity, 2016 - Springer
Rho-associated protein kinase (ROCK) has been recognized as an attractive therapeutic
target to promote neurogenesis, neuroregeneration, and neurorecovery after cerebral injury …
target to promote neurogenesis, neuroregeneration, and neurorecovery after cerebral injury …
Integration of virtual screening and susceptibility test to discover active-site subpocket-specific biogenic inhibitors of Helicobacter pylori shikimate dehydrogenase
K Wang, M Zhu, Y Tang, J Liu, F Yan, Z Yu… - International …, 2019 - Springer
Abstract Shikimate dehydrogenase (HpSDH)(EC 1.1. 1.25) is a key enzyme in the shikimate
pathway of Helicobacter pylori (H. pylori), which catalyzes the NADPH-dependent reversible …
pathway of Helicobacter pylori (H. pylori), which catalyzes the NADPH-dependent reversible …
Formation of new substituted (1, 3) oxazepine 1, 5-diones via reaction of Exo-3, 6-epoxy-1, 2, 3, 6-tetrahydrophthalic Anhydride with Schiff's bases
MG Mukhlif, OJM Al-Asafi, AK Alywee - AIP Conference Proceedings, 2023 - pubs.aip.org
1, 3-oxazepine-1, 5-diones, and its derivatives are quite substantial compounds utilized in
various field like biological activity. Therefore several compounds have been prepared by …
various field like biological activity. Therefore several compounds have been prepared by …
[PDF][PDF] In silico design, synthesis and pharmacological screening of quinazolinones as NMDA receptor antagonists for anticonvulsant activity: part II
Background: N-methyl-D-Aspartate (NMDA) receptor plays a main role in eliptogenisis and
its inhibition has therapeutic significance in development of anticonvulsants. Prioritized …
its inhibition has therapeutic significance in development of anticonvulsants. Prioritized …
Synthesis, characterization and antibacterial activities of new substituted (1, 3) oxazepine 1, 5-diones
M Ghanam, O Mahdi - International Journal of New Chemistry, 2023 - ijnc.ir
Novel Imine were prepared via the reaction of (p-chloro and p-methyl) aniline with (p-nitro
and p-methoxy) benzaldehyde and later engaged in a condensation reaction with 2-O …
and p-methoxy) benzaldehyde and later engaged in a condensation reaction with 2-O …
Synthesis and Characterization of Some Heterocyclic Compounds from 1-amino-2-naphthol-4-sulfonic acid and their antibacterial activity
AA Mahdy, FAH Al-Rammahi - Journal of Kufa for Chemical …, 2018 - journal.uokufa.edu.iq
This research includes synthesized of heterocyclic compounds of the interaction (1-amino-
2-naphthol-4-sulfonic acid) with (isatin, 3-hydroxy-5-methyl benzaldehyde) These …
2-naphthol-4-sulfonic acid) with (isatin, 3-hydroxy-5-methyl benzaldehyde) These …
Spectrum of the neuro-cardio-angiotropic and protector activity of the quinazoline and quinazolinone derivatives
M Manvelyan, E Manvelyan, V Baturin - medvestnik.stgmu.ru
The features of the effect of quinazoline and quinazolinone derivatives with various
substituents on the nervous and cardiovascular systems are considered. Natural and …
substituents on the nervous and cardiovascular systems are considered. Natural and …