In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

Achieving the transition metal-catalysed pyridine C3− H alkenylation, with pyridine as the
limiting reagent, has remained a long-standing challenge. Previously, we disclosed that the …

The activation of ubiquitous C–H bonds has great significance in the field of organic
synthesis given that it represents an ideal method for directly producing valuable chemicals …

Annulated pyridones are an important scaffold found in many biologically active compounds.
A Ni (0)-catalyzed C–H functionalization of 2-and 4-pyridones is disclosed, providing access …

Highly enantioselective nickel‐catalyzed alkene endo‐hydroarylations were accomplished
with full selectivity by organometallic C− H activation. The asymmetric assembly of chiral six …

The asymmetric functionalization of C− H bond is a particularly valuable approach for the
production of enantioenriched chiral organic compounds. Chiral N‐heterocyclic carbene …

Enantioselective Ni‐catalyzed C (sp3)− H bond activation remains an elusive challenge.
Herein, we used phosphine oxide‐ligated Ni− Al bimetallic catalyst to realize …

A unified strategy for nickel (0)‐catalyzed C− H allylations, alkenylations, and dienylations
has been realized through versatile hydroarylations of allenes with ample scope. Thus, an …

The first iron-catalyzed enantioselective Si–H bond insertion reaction of α-diazoesters was
developed. A new chiral spiro-bisoxazoline ligand has proven to be an optimal ligand for the …