Current opportunities and challenges in microbial metagenome analysis—a bioinformatic perspective

H Teeling, FO Glöckner - Briefings in bioinformatics, 2012 - academic.oup.com
Metagenomics has become an indispensable tool for studying the diversity and metabolic
potential of environmental microbes, whose bulk is as yet non-cultivable. Continual progress …

Function, distribution, and annotation of characterized cellulases, xylanases, and chitinases from CAZy

STC Nguyen, HL Freund, J Kasanjian… - Applied microbiology and …, 2018 - Springer
The enzymatic deconstruction of structural polysaccharides, which relies on the production
of specific glycoside hydrolases (GHs), is an essential process across environments. Over …

Characterizing the mucin-degrading capacity of the human gut microbiota

JS Glover, TD Ticer, MA Engevik - Scientific reports, 2022 - nature.com
Mucin-degrading microbes are known to harbor glycosyl hydrolases (GHs) which cleave
specific glycan linkages. Although several microbial species have been identified as mucin …

Rhizosphere microbiome structure alters to enable wilt resistance in tomato

MJ Kwak, HG Kong, K Choi, SK Kwon, JY Song… - Nature …, 2018 - nature.com
Tomato variety Hawaii 7996 is resistant to the soil-borne pathogen Ralstonia solanacearum,
whereas the Moneymaker variety is susceptible to the pathogen. To evaluate whether plant …

dbCAN2: a meta server for automated carbohydrate-active enzyme annotation

H Zhang, T Yohe, L Huang, S Entwistle… - Nucleic acids …, 2018 - academic.oup.com
Complex carbohydrates of plants are the main food sources of animals and microbes, and
serve as promising renewable feedstock for biofuel and biomaterial production …

dbCAN: a web resource for automated carbohydrate-active enzyme annotation

Y Yin, X Mao, J Yang, X Chen, F Mao… - Nucleic acids …, 2012 - academic.oup.com
Carbohydrate-active enzymes (CAZymes) are very important to the biotech industry,
particularly the emerging biofuel industry because CAZymes are responsible for the …

dbCAN-seq: a database of carbohydrate-active enzyme (CAZyme) sequence and annotation

L Huang, H Zhang, P Wu, S Entwistle, X Li… - Nucleic Acids …, 2018 - academic.oup.com
Carbohydrate-active enzyme (CAZymes) are not only the most important enzymes for
bioenergy and agricultural industries, but also very important for human health, in that …

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

P Baker, PJ Hill, BD Snarr, N Alnabelseya… - Science …, 2016 - science.org
Bacterial biofilms present a significant medical challenge because they are recalcitrant to
current therapeutic regimes. A key component of biofilm formation in the opportunistic …

Genome sequencing of four Aureobasidium pullulans varieties: biotechnological potential, stress tolerance, and description of new species

C Gostinčar, RA Ohm, T Kogej, S Sonjak, M Turk, J Zajc… - BMC genomics, 2014 - Springer
Background Aureobasidium pullulans is a black-yeast-like fungus used for production of the
polysaccharide pullulan and the antimycotic aureobasidin A, and as a biocontrol agent in …

Prevalent genome streamlining and latitudinal divergence of planktonic bacteria in the surface ocean

BK Swan, B Tupper, A Sczyrba… - Proceedings of the …, 2013 - National Acad Sciences
Planktonic bacteria dominate surface ocean biomass and influence global biogeochemical
processes, but remain poorly characterized owing to difficulties in cultivation. Using large …