The kidney has the principal role in the maintenance of acid-base balance. Therefore, a
decrease in renal ammonium excretion and a positive acid balance often leading to a …

Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of
cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium …

Mass spectrometry-based proteomic technique has become indispensable in current
exploration of complex and dynamic biological processes. Instrument development has …

Objective Diabetic kidney disease (DKD) is one of the most frequent complications in
diabetes associated with substantial morbidity and mortality. To accelerate DKD risk factor …

Metabolic acidosis is a common complication of chronic kidney disease. Accumulating
evidence identifies acidosis not only as a consequence of, but as a contributor to, kidney …

Background The relationship between albumin corrected anion gap (ACAG) and in-hospital
mortality of intensive care sepsis patients is currently inconclusive. Methods The baseline …

Background. No epidemiological study has investigated the effect of anion gap (AG) on the
prognosis of critically ill patients with acute kidney injury (AKI). Therefore, we aimed to …

The kidneys play a major role in the regulation of acid-base balance by reabsorbing
bicarbonate filtered by the glomeruli and excreting titratable acids and ammonia into the …

BACKGROUND Skeletal muscle maladaptation accompanies chronic kidney disease (CKD)
and negatively affects physical function. Emphasis in CKD has historically been placed on …

Chloride (Cl−) is the major extracellular anion in the body, accompanying sodium (Na+), and
is primarily derived from dietary sources. Data suggest that increased dietary Cl− intake …