Microglia, of myeloid origin, play fundamental roles in the control of immune responses and
the maintenance of central nervous system homeostasis. These cells, just like peripheral …

Stroke is the leading cause of disability and mortality in the world, but the pathogenesis of
ischemic stroke (IS) is not completely clear and treatments are limited. Mounting evidence …

Mesenchymal stem cells (MSCs) have been found to benefit patients with a variety of
ischemic diseases via promoting angiogenesis. It is also well established that exosomes …

The nuclear translocation and activity of the cotranscriptional activators YAP and TAZ
(YAP/TAZ) in endothelial cells (ECs) are crucial during developmental angiogenesis. Here …

Background Small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSC)
derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to …

Angiogenesis is a complicated and sequential process that plays an important role in
different physiological processes. Mesenchymal stem cells (MSCs), which are pluripotent …

Angiogenesis plays an important role in the remodeling process of the ischemic brain and
the recovery of neurological function after ischemic stroke. Ginsenoside Rg1 has been …

Rationale: Angiogenesis promotes neurological recovery after stroke and is associated with
longer survival of stroke patients. Cerebral angiogenesis is tightly controlled by certain …

Owing to its high disability and mortality rates, stroke has been the second leading cause of
death worldwide. Since the pathological mechanisms of stroke are not fully understood …

The Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3)
signaling pathway, a well-conserved and basic intracellular signaling cascade, is mostly …