Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM

CC Chang, TS Harrison, TA Bicanic… - The Lancet Infectious …, 2024 - thelancet.com
Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis,
particularly in its most lethal manifestation of cryptococcal meningitis, accounts for …

Advanced HIV: diagnosis, treatment, and prevention

S Prabhu, JI Harwell, N Kumarasamy - The lancet HIV, 2019 - thelancet.com
Substantial progress has been made this century in bringing millions of people living with
HIV into care, but progress for early HIV diagnosis has stalled. Individuals first diagnosed …

Why the HIV reservoir never runs dry: clonal expansion and the characteristics of HIV-infected cells challenge strategies to cure and control HIV infection

CY Lau, MA Adan, F Maldarelli - Viruses, 2021 - mdpi.com
Antiretroviral therapy (ART) effectively reduces cycles of viral replication but does not target
proviral populations in cells that persist for prolonged periods and that can undergo clonal …

Biomarkers of mortality in adults and adolescents with advanced HIV in sub-Saharan Africa

V Riitho, R Connon, A Gwela, J Namusanje… - Nature …, 2024 - nature.com
One-third of people with HIV in sub-Saharan Africa start antiretroviral therapy (ART) with
advanced disease. We investigated associations between immune biomarkers and mortality …

Prevalence, characteristics and challenges of late HIV diagnosis in Germany: an expert narrative review

C Boesecke, S Schellberg, J Schneider, G Schuettfort… - Infection, 2023 - Springer
Purpose We aimed to review the landscape of late HIV diagnosis in Germany and discuss
persisting and emerging barriers to earlier diagnosis alongside potential solutions. Methods …

Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic review

CL Townsend, J O'Rourke, E Milanzi… - Journal of the …, 2022 - Wiley Online Library
Introduction Globally about 1.7 million children were living with HIV in 2020. Two integrase
strand transfer inhibitors, dolutegravir and raltegravir, are increasingly used in children. We …

Immune reconstitution inflammatory syndrome in HIV infected late presenters starting integrase inhibitor containing antiretroviral therapy

IEA Wijting, FWNM Wit, C Rokx, EMS Leyten… - …, 2019 - thelancet.com
Background Integrase inhibitors (INI) induce a rapid decline of HIV-RNA in plasma and
CD4+ T-cell recovery in blood. Both characteristics are also associated with immune …

Risk of immune reconstitution inflammatory syndrome with integrase inhibitors versus other classes of antiretrovirals: a systematic review and meta-analysis of …

Y Zhao, A Hohlfeld, P Namale, G Meintjes… - JAIDS Journal of …, 2022 - journals.lww.com
Background: Integrase strand transfer inhibitors (InSTIs) decrease HIV plasma viral load
faster than other antiretroviral classes. More rapid viral load decline has been associated …

Combination antiretroviral therapy and hypertensive disorders of pregnancy

MK Saums, CC King, JC Adams, AN Sheth… - Obstetrics & …, 2019 - journals.lww.com
OBJECTIVE: To compare the incidence of hypertensive disorders of pregnancy among
women living with human immunodeficiency virus (HIV) on combination antiretroviral …

Immune reconstitution inflammatory syndrome associated Kaposi sarcoma

I Poizot-Martin, S Brégigeon, R Palich, AG Marcelin… - Cancers, 2022 - mdpi.com
Simple Summary Kaposi sarcoma (KS) incidence has declined substantially since the
advent of effective ART but it remains a frequent cancer among people living with HIV …