Mitochondria, known for more than a century as the energy powerhouse of a cell, represent
key intracellular signaling hub that are emerging as important determinants of several …

Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

The study of cell-population heterogeneity in a range of biological systems, from viruses to
bacterial isolates to tumor samples, has been transformed by recent advances in …

Rewiring of energy metabolism and adaptation of mitochondria are considered to impact on
prostate cancer development and progression. Here, we report on mitochondrial respiration …

Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death.
Thus, new strategies to deal with the evasion of drug response and to improve clinical …

The acute cellular response to stress generates a subpopulation of reversibly stress-tolerant
cells under conditions that are lethal to the majority of the population. Stress tolerance is …

Mitochondria, well recognized as the “powerhouse” of cells, are maternally inherited
organelles with bacterial ancestry that play essential roles in a myriad of cellular functions. It …

Simple Summary Cancer cells are dependent on normal cells for their survival and
functionality because they can use nanoscale tubes to steal the mitochondria from immune …

Nuclear mutations are well known to drive tumor incidence, aggression and response to
therapy. By contrast, the frequency and roles of mutations in the maternally inherited …

Mitochondria from normal and cancerous cells represent a tale of two cities, wherein both
execute similar processes but with different cellular and molecular effects. Given the number …