Non-thermal plasma as a novel strategy for treating or preventing viral infection and associated disease

H Mohamed, G Nayak, N Rendine, B Wigdahl… - Frontiers in …, 2021 - frontiersin.org
Pathogenic viruses cause many human, animal, and plant diseases that are associated with
substantial morbidity, mortality and socio-economic impact. Although effective strategies for …

Safety and potency of BIV1‐CovIran inactivated vaccine candidate for SARS‐CoV‐2: A preclinical study

A Abdoli, R Aalizadeh, H Aminianfar… - Reviews in medical …, 2022 - Wiley Online Library
The development of effective and safe COVID‐19 vaccines is a major move forward in our
global effort to control the SARS‐CoV‐2 pandemic. The aims of this study were (1) to …

Innate immune sensing of influenza A virus

G Malik, Y Zhou - Viruses, 2020 - mdpi.com
Influenza virus infection triggers host innate immune response by stimulating various pattern
recognition receptors (PRRs). Activation of these PRRs leads to the activation of a plethora …

Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1

I Ramos, G Smith, F Ruf-Zamojski… - Journal of …, 2019 - Am Soc Microbiol
Early interactions of influenza A virus (IAV) with respiratory epithelium might determine the
outcome of infection. The study of global cellular innate immune responses often masks …

Antiviral activity of furanocoumarins isolated from Angelica dahurica against influenza a viruses H1N1 and H9N2

BW Lee, TKQ Ha, HM Cho, JP An, SK Kim… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Angelica dahurica (Hoffm.) Benth. & Hook. f. ex
Franch. & Sav.(Umbelliferae family) is an herbaceous, perennial plant native to northern and …

Pathogen population bottlenecks and adaptive landscapes: overcoming the barriers to disease emergence

JL Geoghegan, AM Senior… - Proceedings of the …, 2016 - royalsocietypublishing.org
Emerging diseases are a major challenge to public health. Revealing the evolutionary
processes that allow novel pathogens to adapt to new hosts, also the potential barriers to …

Intranasal administration of cold-adapted live-attenuated SARS-CoV-2 candidate vaccine confers protection against SARS-CoV-2

M Abdoli, M Shafaati, LK Ghamsari, A Abdoli - Virus Research, 2022 - Elsevier
With the COVID-19 pandemic globally, the ongoing threat of new challenges of mucosal
infections was once again reminded human beings. Hence, access to the next-generation …

Autophagy induction regulates influenza virus replication in a time-dependent manner

N Feizi, P Mehrbod, B Romani… - Journal of medical …, 2017 - microbiologyresearch.org
Purpose. Autophagy plays a key role in host defence responses against microbial infections
by promoting degradation of pathogens and participating in acquired immunity. The …

Molecular epidemiology of the hemagglutinin gene of prevalent influenza virus A/H1N1/pdm09 among patient in Iran

A Mohebbi, F Fotouhi, A Jamali, R Yaghobi… - Virus research, 2019 - Elsevier
In 2015, the influenza virus A/H1N1/pdm09 strain outbreak became prevalent throughout the
different provinces of Iran. There are relatively limited complete genetic sequences available …

Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for …

JN Kelly, L Laloli, P V'kovski, M Holwerda… - Frontiers in …, 2022 - frontiersin.org
The respiratory epithelium constitutes the first line of defense against invading respiratory
pathogens, such as the 2009 pandemic strain of influenza A virus (IAV, H1N1pdm09), and …