Lupus nephritis (LN) is one of the most frequent and severe manifestations of systemic lupus
erythematosus (SLE), considered as the major predictor of poor prognosis. An early …

Background The incidence of pediatric inflammatory bowel disease (PIBD) has been
steadily increasing globally. Delayed diagnosis of PIBD increases the risk of complications …

Introduction IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-
deficient IgA1 and complement proteins and leads to renal impairment. Complement …

Ficolins are pattern-recognition molecules (PRMs) that could form complexes with mannose-
binding lectin-associated serine proteases (MASPs) to trigger complement activation via the …

Objective. The pathogenesis of systemic lupus erythematosus (SLE) involves complement
activation. Activation of complement through the classical pathway (CP) is well established …

Objective Systemic lupus erythematosus (SLE) is a multisystem inflammatory disease
characterized by the production of various autoantibodies. The aim of this study was to …

Abstract Background: IgA nephropathy (IgAN) is the most frequently occurring primary
glomerulonephritis. A lack of specific biomarkers hinders the early diagnosis and treatment …

Objective: The aim of this study was to investigate whether incident proteinuria in patients
with systemic lupus erythematosus (SLE) was preceded by changes in blood lymphocytes …

Pattern recognition molecules (PRMs) in the complement system contribute to homeostasis
as mediators of complement activation. The contribution of PRMs to primary biliary …

Background Pediatric-onset SLE (pSLE) is a multisystem autoimmune disease. Recently,
the ficolin-2 (FCN2) gene has emerged as a potential candidate gene for susceptibility to …