Importance Research has shown an association between opioid prescribing after major or
minor procedures and new persistent opioid use. However, the association of opioid …

Background Given the increased attention to the opioid epidemic and the role of
inappropriate prescribing, there has been a marked increase in the number of studies using …

Objective To determine whether the adoption of laws that limit opioid prescribing or
dispensing is associated with changes in the volume of opioids distributed in states …

Purpose To examine the prevalence of rapid discontinuation of chronic, high-dose opioid
analgesic treatment, and identify associated patient, clinician, and community factors …

Abstract Objective In 2016, the Center for Disease Control and Prevention released an
opioid prescribing guideline for primary care in response to opioid overdose deaths. Despite …

Introduction Concurrent use of prescription opioids with gabapentinoids may pose risks of
serious drug interactions. Yet, little is known about the trends in and patient characteristics …

Background The association between surgeon prescribing practices and new persistent
postoperative opioid use is not well understood. We examined the association between …

Background Both increases and decreases in patients' prescribed daily opioid dose have
been linked to increased overdose risk, but associations between 30-day dose trajectories …

The incidences of herpes zoster (HZ) and postherpetic neuralgia (PHN) are significantly
influenced by age. As individuals age, the occurrence of spinal disorders increases, thereby …

Abstract In the United States, more than 100 million people suffer from chronic pain. Among
patients presenting for surgery, about one in four have chronic pain. Acute perioperative …