Antivirals targeting paramyxovirus membrane fusion

EM Contreras, IA Monreal, M Ruvalcaba… - Current opinion in …, 2021 - Elsevier
The Paramyxoviridae family includes enveloped single-stranded negative-sense RNA
viruses such as measles, mumps, human parainfluenza, canine distemper, Hendra, and …

A neutralizing antibody prevents postfusion transition of measles virus fusion protein

DS Zyla, R Della Marca, G Niemeyer, G Zipursky… - Science, 2024 - science.org
Measles virus (MeV) presents a public health threat that is escalating as vaccine coverage in
the general population declines and as populations of immunocompromised individuals …

Relationship of human cytomegalovirus‐infected endothelial cells and circulating leukocytes in the pathogenesis of disseminated human cytomegalovirus infection: A …

G Gerna, D Lilleri, C Fornara… - Reviews in Medical …, 2024 - Wiley Online Library
Among the leucocyte subpopulations circulating in peripheral blood of immune‐
compromised patients with disseminated Human cytomegalovirus (HCMV) infection …

Inhibition of measles viral fusion is enhanced by targeting multiple domains of the fusion protein

FT Bovier, K Rybkina, S Biswas, O Harder… - ACS …, 2021 - ACS Publications
Measles virus (MeV) infection remains a significant public health threat despite ongoing
global efforts to increase vaccine coverage. As eradication of MeV stalls, and vulnerable …

Viral and cellular factors contributing to the hematogenous dissemination of human cytomegalovirus via polymorphonuclear leukocytes

B Braun, K Laib Sampaio, AK Kuderna, M Widmann… - Viruses, 2022 - mdpi.com
Polymorphonuclear leukocytes (PMNs) presumably transmit human cytomegalovirus
(HCMV) between endothelial cells in blood vessels and thereby facilitate spread to …