[HTML][HTML] Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit
F Brites, M Martin, I Guillas, A Kontush - BBA clinical, 2017 - Elsevier
Uptake of low-density lipoprotein (LDL) particles by macrophages represents a key step in
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …
the development of atherosclerotic plaques, leading to the foam cell formation. Chemical …
Effect of statin therapy on paraoxonase-1 status: a systematic review and meta-analysis of 25 clinical trials
Background Decreased activity of the enzyme paraoxonase-1 (PON1) has been
demonstrated in cardiovascular diseases. Statins, the forefront of pharmacotherapy for …
demonstrated in cardiovascular diseases. Statins, the forefront of pharmacotherapy for …
Paraoxonase 1 and atherosclerosis‐related diseases
J Kotur‐Stevuljević, J Vekić, A Stefanović… - Biofactors, 2020 - Wiley Online Library
A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …
Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on
LG Costa, G Giordano, CE Furlong - Biochemical pharmacology, 2011 - Elsevier
Paraoxonase 1 (PON1) is a high density lipoprotein (HDL)-associated enzyme displaying
esterase and lactonase activity. PON1 hydrolyzes several organophosphorus (OP) …
esterase and lactonase activity. PON1 hydrolyzes several organophosphorus (OP) …
Variation in paraoxonase-1 activity and atherosclerosis
Variation in paraoxonase-1 activity and atherosclerosis : Current Opinion in Lipidology
Variation in paraoxonase-1 activity and atherosclerosis : Current Opinion in Lipidology Log in or …
Variation in paraoxonase-1 activity and atherosclerosis : Current Opinion in Lipidology Log in or …
The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation
Abstract Background Paraoxonase 1 (PON1) is an important antiatherogenic and
antioxidant enzyme in the circulation that has been associated with adverse health …
antioxidant enzyme in the circulation that has been associated with adverse health …
[HTML][HTML] Effect of carotenoids on paraoxonase-1 activity and gene expression
A Otocka-Kmiecik - Nutrients, 2022 - mdpi.com
Paraoxonase 1 (PON1) is an antioxidant enzyme attached to HDL with an anti-atherogenic
potential. It protects LDL and HDL from lipid peroxidation. The enzyme is sensitive to various …
potential. It protects LDL and HDL from lipid peroxidation. The enzyme is sensitive to various …
HDL and Oxidation
Q Zhang, Z Jiang, Y Xu - HDL Metabolism and Diseases, 2022 - Springer
In this chapter, we will focus on HDLs' activity of inhibiting LDL oxidation and neutralizing
some other oxidants. ApoA-I was known as the main antioxidant component in HDLs. The …
some other oxidants. ApoA-I was known as the main antioxidant component in HDLs. The …
Role of paraoxonase1 in the regulation of high-density lipoprotein functionality and in cardiovascular protection
A Khalil, T Fulop, H Berrougui - Antioxidants & redox signaling, 2021 - liebertpub.com
Significance: Human paraoxonase (PON) is a member of the gene family that includes
paraoxonase 1 (PON1), PON2, and PON3. PON is known for its capacity to hydrolyze a wide …
paraoxonase 1 (PON1), PON2, and PON3. PON is known for its capacity to hydrolyze a wide …
Pharmacogenetics of paraoxonase activity: elucidating the role of high-density lipoprotein in disease
PON1 is a key component of high-density lipoproteins (HDLs) and is at least partially
responsible for HDL's antioxidant/atheroprotective properties. PON1 is also associated with …
responsible for HDL's antioxidant/atheroprotective properties. PON1 is also associated with …