Semi-implantable bioelectronics

J Fang, S Huang, F Liu, G He, X Li, X Huang, H Chen… - Nano-Micro Letters, 2022 - Springer
Developing techniques to effectively and real-time monitor and regulate the interior
environment of biological objects is significantly important for many biomedical engineering …

Single-component near-infrared optogenetic systems for gene transcription regulation

AA Kaberniuk, M Baloban, MV Monakhov… - Nature …, 2021 - nature.com
Near-infrared (NIR) optogenetic systems for transcription regulation are in high demand
because NIR light exhibits low phototoxicity, low scattering, and allows combining with …

Multi-neuron intracellular recording in vivo via interacting autopatching robots

SB Kodandaramaiah, FJ Flores, GL Holst, AC Singer… - Elife, 2018 - elifesciences.org
The activities of groups of neurons in a circuit or brain region are important for neuronal
computations that contribute to behaviors and disease states. Traditional extracellular …

[HTML][HTML] In vitro comparative analysis of human dental stem cells from a single donor and its neuronal differentiation potential evaluated by electrophysiology

I Ullah, RB Subbarao, EJ Kim, D Bharti, SJ Jang… - Life sciences, 2016 - Elsevier
Aims The aim of this study was to find out a mesenchymal stem cells (MSCs) source from
human dental tissues of the same donor (follicle, papilla and pulp), which exhibits higher …

Assembly and operation of the autopatcher for automated intracellular neural recording in vivo

SB Kodandaramaiah, GL Holst, IR Wickersham… - Nature protocols, 2016 - nature.com
Whole-cell patch clamping in vivo is an important neuroscience technique that uniquely
provides access to both suprathreshold spiking and subthreshold synaptic events of single …

Hard real-time closed-loop electrophysiology with the Real-Time eXperiment Interface (RTXI)

YA Patel, A George, AD Dorval, JA White… - PLoS computational …, 2017 - journals.plos.org
The ability to experimentally perturb biological systems has traditionally been limited to static
pre-programmed or operator-controlled protocols. In contrast, real-time control allows …

HiPSC-derived retinal ganglion cells grow dendritic arbors and functional axons on a tissue-engineered scaffold

K Li, X Zhong, S Yang, Z Luo, K Li, Y Liu, S Cai, H Gu… - Acta biomaterialia, 2017 - Elsevier
Numerous therapeutic procedures in modern medical research rely on the use of tissue
engineering for the treatment of retinal diseases. However, the cell source and the …

PatcherBot: a single-cell electrophysiology robot for adherent cells and brain slices

I Kolb, CR Landry, MC Yip, CF Lewallen… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Intracellular patch-clamp electrophysiology, one of the most ubiquitous, high-
fidelity techniques in biophysics, remains laborious and low-throughput. While previous …

A 155-dB dynamic range current measurement front end for electrochemical biosensing

S Dai, RT Perera, Z Yang… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
An integrated current measurement system with ultra wide dynamic range is presented and
fabricated in a 180-nm CMOS technology. Its dual-mode design provides concurrent voltage …

Functional studies of sodium channels: from target to compound identification

D Bertrand, B Biton, T Licher… - Current Protocols in …, 2016 - Wiley Online Library
Over the last six decades, voltage‐gated sodium (Nav) channels have attracted a great deal
of scientific and pharmaceutical interest, driving fundamental advances in both biology and …