Semi-implantable bioelectronics
Developing techniques to effectively and real-time monitor and regulate the interior
environment of biological objects is significantly important for many biomedical engineering …
environment of biological objects is significantly important for many biomedical engineering …
Single-component near-infrared optogenetic systems for gene transcription regulation
Near-infrared (NIR) optogenetic systems for transcription regulation are in high demand
because NIR light exhibits low phototoxicity, low scattering, and allows combining with …
because NIR light exhibits low phototoxicity, low scattering, and allows combining with …
Multi-neuron intracellular recording in vivo via interacting autopatching robots
The activities of groups of neurons in a circuit or brain region are important for neuronal
computations that contribute to behaviors and disease states. Traditional extracellular …
computations that contribute to behaviors and disease states. Traditional extracellular …
[HTML][HTML] In vitro comparative analysis of human dental stem cells from a single donor and its neuronal differentiation potential evaluated by electrophysiology
Aims The aim of this study was to find out a mesenchymal stem cells (MSCs) source from
human dental tissues of the same donor (follicle, papilla and pulp), which exhibits higher …
human dental tissues of the same donor (follicle, papilla and pulp), which exhibits higher …
Assembly and operation of the autopatcher for automated intracellular neural recording in vivo
Whole-cell patch clamping in vivo is an important neuroscience technique that uniquely
provides access to both suprathreshold spiking and subthreshold synaptic events of single …
provides access to both suprathreshold spiking and subthreshold synaptic events of single …
Hard real-time closed-loop electrophysiology with the Real-Time eXperiment Interface (RTXI)
The ability to experimentally perturb biological systems has traditionally been limited to static
pre-programmed or operator-controlled protocols. In contrast, real-time control allows …
pre-programmed or operator-controlled protocols. In contrast, real-time control allows …
HiPSC-derived retinal ganglion cells grow dendritic arbors and functional axons on a tissue-engineered scaffold
Numerous therapeutic procedures in modern medical research rely on the use of tissue
engineering for the treatment of retinal diseases. However, the cell source and the …
engineering for the treatment of retinal diseases. However, the cell source and the …
PatcherBot: a single-cell electrophysiology robot for adherent cells and brain slices
Objective. Intracellular patch-clamp electrophysiology, one of the most ubiquitous, high-
fidelity techniques in biophysics, remains laborious and low-throughput. While previous …
fidelity techniques in biophysics, remains laborious and low-throughput. While previous …
A 155-dB dynamic range current measurement front end for electrochemical biosensing
An integrated current measurement system with ultra wide dynamic range is presented and
fabricated in a 180-nm CMOS technology. Its dual-mode design provides concurrent voltage …
fabricated in a 180-nm CMOS technology. Its dual-mode design provides concurrent voltage …
Functional studies of sodium channels: from target to compound identification
D Bertrand, B Biton, T Licher… - Current Protocols in …, 2016 - Wiley Online Library
Over the last six decades, voltage‐gated sodium (Nav) channels have attracted a great deal
of scientific and pharmaceutical interest, driving fundamental advances in both biology and …
of scientific and pharmaceutical interest, driving fundamental advances in both biology and …