Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix,
behaving as a critical mechanism in preventing adherent-independent cell growth and …

Metastasis is a phenomenon of crucial importance in defining prognosis in patients with
cancer and is often responsible for cancer-related mortality. It is known that several steps are …

Purpose: PARP inhibitors (PARPi) are primarily effective against BRCA1/2-mutated breast
and ovarian cancers, but resistance due to reversion of mutated BRCA1/2 and other …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

In this study we performed a systematic evaluation of functional miRNA-mRNA interactions
associated with the invasiveness of breast cancer cells using a combination of integrated …

Metastasis is the predominant cause of death in breast cancer patients. Several lines of
evidence have shown that microRNAs (miRs) can have an important role in cancer …

MicroRNAs (miRNAs) are considered to be regulators of various biological processes in
cancers, including the epithelial to mesenchymal transition (EMT), which is a key factor in …

Abstract MicroRNAs (miRNAs) are short (22 nucleotides), single-stranded, non-coding
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …

Abstract The miR-19 family (miR-19a and miR-19b-1) are key oncogenic components of the
miR-17-92 cluster. Overexpression of miR-19 is strongly associated with cancer invasion …

Epithelial-to-mesenchymal transition (EMT) is a collection of events that allows the
conversion of adherent epithelial cells, tightly bound to each other within an organized …