Challenges and opportunities in cryo-EM single-particle analysis
D Lyumkis - Journal of Biological Chemistry, 2019 - ASBMB
Cryogenic electron microscopy (cryo-EM) enables structure determination of
macromolecular objects and their assemblies. Although the techniques have been …
macromolecular objects and their assemblies. Although the techniques have been …
Development of a new protein labeling system to map subunits and domains of macromolecular complexes for electron microscopy
ZP Brown, T Arimori, K Iwasaki, J Takagi - Journal of structural biology, 2018 - Elsevier
Several gene fusion technologies have been successfully applied to label particular
subunits or domains within macromolecular complexes to enable positional mapping of …
subunits or domains within macromolecular complexes to enable positional mapping of …
Advances in domain and subunit localization technology for electron microscopy
ZP Brown, J Takagi - Biophysical Reviews, 2019 - Springer
The award of the 2017 Nobel Prize in chemistry,'for developing cryo-electron microscopy for
the high-resolution structure determination of biomolecules in solution', was recognition that …
the high-resolution structure determination of biomolecules in solution', was recognition that …
Cryo‐EM of dynamic protein complexes in eukaryotic DNA replication
DNA replication in Eukaryotes is a highly dynamic process that involves several dozens of
proteins. Some of these proteins form stable complexes that are amenable to high …
proteins. Some of these proteins form stable complexes that are amenable to high …
[PDF][PDF] Structural and biochemical insights into the ATP-dependent chromatin remodeler LSH
S Varzandeh - 2017 - core.ac.uk
Chromatin remodelling proteins support a variety of cellular functions and utilise the energy
from ATP hydrolysis to either reposition or evict nucleosomes. One such protein, Lymphoid …
from ATP hydrolysis to either reposition or evict nucleosomes. One such protein, Lymphoid …
Evaluation der Tumormarker TKTL1, Apo10 und GD2 in Rhabdomyosarkom-und Neuroblastom-Tumoren
MJ Stagno - 2020 - ub01.uni-tuebingen.de
Das Rhabdomyosarkom (RMS) und das Neuroblastom (NB) gehören zu den häufigsten
extrakranialen, soliden Tumoren im Kindesalter. Dabei beruhen Tumorstaging, Diagnose …
extrakranialen, soliden Tumoren im Kindesalter. Dabei beruhen Tumorstaging, Diagnose …
Fluoreszenzmarkierung und Modifizierung von komplexen Proteinen in eukaryotischen zellfreien Systemen durch die Etablierung von orthogonalen tRNA/Aminoacyl …
A Zemella - 2019 - publishup.uni-potsdam.de
Die funktionelle Charakterisierung von therapeutisch relevanten Proteinen kann bereits
durch die Bereitstellung des Zielproteins in adäquaten Mengen limitierend sein. Dies trifft …
durch die Bereitstellung des Zielproteins in adäquaten Mengen limitierend sein. Dies trifft …
[图书][B] Illuminating degradation: The coordination and timing of substrate processing by the 26S proteasome
J Bard - 2018 - search.proquest.com
Selective protein degradation is a constant and critical process in cells. It is essential for
maintaining tight control over protein abundance, which allows for finely tuned regulatory …
maintaining tight control over protein abundance, which allows for finely tuned regulatory …