Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Although chemotherapy can improve the overall survival and prognosis of cancer patients,
chemoresistance remains an obstacle due to the diversity, heterogeneity, and adaptability to …

The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

The SLC2 genes code for a family of GLUT proteins that are part of the major facilitator
superfamily (MFS) of membrane transporters. Crystal structures have recently revealed how …

As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …

It is long recognized that cancer cells display increased glucose uptake and metabolism. In
a rate-limiting step for glucose metabolism, the glucose transporter (GLUT) proteins facilitate …

An important hallmark in cancer cells is the increase in glucose uptake. GLUT1 is an
important target in cancer treatment because cancer cells upregulate GLUT1, a membrane …

It has been known for 80years that cancer cell growth in an energy-related process
supported by an increased glucose metabolism. This phenomenon suggests a need for a …

Malignant cells are known to have accelerated metabolism, high glucose requirements, and
increased glucose uptake. Transport of glucose across the plasma membrane of …

Tumor cells have an increased demand for nutrients; this demand is met by increased
availability of nutrients through vasculogenesis and by enhanced cellular entry of nutrients …