The hypothalamic-pituitary adrenal axis is a complex system of neuroendocrine pathways
and feedback loops that function to maintain physiological homeostasis. Abnormal …

Coping with stress is fundamental for mental health, but understanding of the molecular
neurobiology of stress is still in its infancy. Adult neurogenesis is well known to be regulated …

The hypothalamic‐pituitary‐adrenal (HPA) axis regulates circulating levels of glucocorticoid
hormones, and is the major neuroendocrine system in mammals that provides a rapid …

Glucocorticoids (GCs) are secreted in an ultradian, pulsatile pattern that emerges from
delays in the feedforward-feedback interaction between the anterior pituitary and adrenal …

Chronic insomnia is highly prevalent and associated with significant morbidity (ie, confers
risk for multiple psychiatric and medical disorders, such as depression and hypertension) …

Glucocorticoids, vertebrate steroid hormones produced by cells of the adrenal cortex or
interrenal tissue, function dynamically to maintain homeostasis under constantly changing …

This is a book about 'Neurodynamics'. What we mean is that this is a book about how ideas
from dynamical systems theory have been developed and employed in recent years to give …

The hypothesis that rapid glucocorticoid inhibition of pituitary ACTH secretion mediates a
feedforward/feedback mechanism responsible for the hourly glucocorticoid pulsatility was …

Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex
and heterogeneous etiology. Most treatments take weeks to show effects and work well only …

Oscillations are a fundamental feature of neural and endocrine systems. The hypothalamic-
pituitary-adrenal (HPA) axis dynamically controls corticosteroid secretion in basal conditions …