Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

The gut microbiome produces chemically diverse small molecules to interact with the host,
conveying signals from the gut to the whole system. The microbial metabolites feature …

Ongoing social, political and ecological changes in the 21st century have placed more
people at risk of life-threatening acute and chronic infections than ever before. The …

The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals including C. trachomatis and C. pneumoniae. Since 1998, when the …

Pathogenic intracellular bacteria, parasites and viruses have evolved sophisticated
mechanisms to manipulate mammalian host cells to serve as niches for persistence and …

Intracellular human pathogens are the deadliest infectious diseases and pose great difficulty
to effectively treat due to their protection inside the host cell and the development of …

Chlamydia trachomatis (Ctr) causes a range of infectious diseases and is epidemiologically
associated with cervical and ovarian cancers. To obtain a panoramic view of Ctr-induced …

Chlamydia trachomatis infection of the human fallopian tubes can lead to damaging
inflammation and scarring, ultimately resulting in infertility. To study the human cellular …

Chlamydia trachomatis is an obligate intracellular bacterium that scavenges host metabolic
products for its replication. Mitochondria are the power plants of eukaryotic cells and provide …