Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches
M Shi, Z Chen, H Gong, Z Peng, Q Sun… - Phytotherapy …, 2024 - Wiley Online Library
Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …
A review on the neurotoxic effects of doxorubicin
K Kamińska, A Cudnoch-Jędrzejewska - Neurotoxicity Research, 2023 - Springer
Anthracyclines, a class of drugs considered as most effective anticancer drugs, used in the
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
Luteolin Mitigates D-Galactose-Induced Brain Ageing in Rats: SIRT1-Mediated Neuroprotection
RL Younis, RM El-Gohary, AA Ghalwash… - Neurochemical …, 2024 - Springer
Luteolin is an essential natural polyphenol found in a variety of plants. Numerous studies
have supported its protective role in neurodegenerative diseases, yet the research for its …
have supported its protective role in neurodegenerative diseases, yet the research for its …
Rational design of copper (i)-doped metal–organic frameworks as dual-functional nanocarriers for combined chemo–chemodynamic therapy
L Yao, B Chen, H Wu, Y Cui, G Qian - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Combination therapies are an increasingly important part of the antitumor medicine
armamentarium. However, developing desirable nanomaterials for combination therapies is …
armamentarium. However, developing desirable nanomaterials for combination therapies is …
Dose-dependent manner of luteolin in the modulation of spatial memory with respect to the hippocampal level of HSP70 and HSP90 in sleep-deprived rats
Sleep deprivation (SD) induces a variety of deleterious effects on different cognitive
functions such as memory. Elevated neuroinflammation, oxidative stress, and apoptosis, and …
functions such as memory. Elevated neuroinflammation, oxidative stress, and apoptosis, and …
Epirubicin toxicity in rat's ovary and uterus: A protective role of 3-Indolepropionic acid supplementation
SE Owumi, GE Adebisi, OA Odunola - Chemico-Biological Interactions, 2023 - Elsevier
Abstract The “anthracycline, Epirubicin (EPI),” in managing breast cancer, is highly cytotoxic.
Tryptophan-derived 3-indolepropionic acid (3-IPA) decreases oxidative damage, and its …
Tryptophan-derived 3-indolepropionic acid (3-IPA) decreases oxidative damage, and its …
Phytochemicals, Biological Activities, Molecular Mechanisms, and Future Prospects of Plantago asiatica L.
SY Wen, BY Wei, JQ Ma, L Wang… - Journal of Agricultural …, 2022 - ACS Publications
Plantago asiatica L. has been used as a vegetable and nutritious food in Asia for thousands
of years. According to recent phytochemical and pharmacological research, the active …
of years. According to recent phytochemical and pharmacological research, the active …
Accidental lead in contaminated pipe-borne water and dietary furan intake perturbs rats' hepatorenal function altering oxidative, inflammatory, and apoptotic balance
Inadvertent exposure to furan and Pb is associated with hepatorenal abnormalities in
humans and animals. It is perceived that these two chemical species may work in synergy to …
humans and animals. It is perceived that these two chemical species may work in synergy to …
Potential of Natural Phenolic Compounds against Doxorubicin-Induced Chemobrain: Biological and Molecular Mechanisms Involved
S Serini, G Calviello - Antioxidants, 2024 - mdpi.com
Chemotherapy-induced cognitive impairment or “chemobrain” is a prevalent long-term
complication of chemotherapy and one of the more devastating. Most of the studies …
complication of chemotherapy and one of the more devastating. Most of the studies …
Natural products for the treatment of chemotherapy-related cognitive impairment and prospects of nose-to-brain drug delivery
YQ He, CC Zhou, SG Jiang, WQ Lan, F Zhang… - Frontiers in …, 2024 - frontiersin.org
Chemotherapy-related cognitive deficits (CRCI) as one of the common adverse drug
reactions during chemotherapy that manifest as memory, attention, and executive function …
reactions during chemotherapy that manifest as memory, attention, and executive function …