Older adult participation in cancer clinical trials: a systematic review of barriers and interventions
MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …
persons with cancer is increasing and will make up a growing share of the oncology …
Improved targeting of cancer care for older patients: a systematic review of the utility of comprehensive geriatric assessment
A Ramjaun, MO Nassif, S Krotneva, AR Huang… - Journal of geriatric …, 2013 - Elsevier
A comprehensive geriatric assessment (CGA) provides clinicians with detailed information
on a patient's physiological age and may aid in the treatment decision-making process …
on a patient's physiological age and may aid in the treatment decision-making process …
Representation of people with comorbidity and multimorbidity in clinical trials of novel drug therapies: an individual-level participant data analysis
Background Clinicians are less likely to prescribe guideline-recommended treatments to
people with multimorbidity than to people with a single condition. Doubts as to the …
people with multimorbidity than to people with a single condition. Doubts as to the …
Impact of age and comorbidity on non–small-cell lung cancer treatment in older veterans
S Wang, ML Wong, N Hamilton, JB Davoren… - Journal of Clinical …, 2012 - ascopubs.org
Purpose Because comorbidity affects cancer treatment outcomes, guidelines recommend
considering comorbidity when making treatment decisions in older patients with lung cancer …
considering comorbidity when making treatment decisions in older patients with lung cancer …
Actual survival after resection of primary colorectal cancer: results from a prospective multicenter study
I van den Berg, RRJ Coebergh van den Braak… - World journal of surgical …, 2021 - Springer
Background Colorectal cancer is the third most common type of cancer in the world. We
characterize a cohort of patients who survived up to 5 years without recurrence and identify …
characterize a cohort of patients who survived up to 5 years without recurrence and identify …
Modified frailty index predicts postoperative outcomes in older gastrointestinal cancer patients
SA Vermillion, FC Hsu, RD Dorrell… - Journal of surgical …, 2017 - Wiley Online Library
Background and Objectives Frailty disproportionately impacts older patients with
gastrointestinal cancer, rendering them at increased risk for poor outcomes. A frailty index …
gastrointestinal cancer, rendering them at increased risk for poor outcomes. A frailty index …
Survey of oncologists' perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials
AB Kornblith, M Kemeny, BL Peterson, J Wheeler… - Cancer, 2002 - Wiley Online Library
BACKGROUND Prior research has documented the under‐representation in clinical trials of
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …
[HTML][HTML] Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: a subgroup analysis from the AGITG MAX trial: an …
Background In an ageing population, a greater proportion of geriatric patients will be
considered for systemic chemotherapy. Colorectal cancer (CRC) is a common malignancy …
considered for systemic chemotherapy. Colorectal cancer (CRC) is a common malignancy …
Community oncologists' decision-making for treatment of older patients with cancer
SG Mohile, A Magnuson, C Pandya, C Velarde… - Journal of the National …, 2018 - jnccn.org
Background: This study's objectives were to describe community oncologists' beliefs about
and confidence with geriatric care and to determine whether geriatric-relevant information …
and confidence with geriatric care and to determine whether geriatric-relevant information …
Treatment of colorectal cancer in older patients
RA Audisio, D Papamichael - Nature Reviews Gastroenterology & …, 2012 - nature.com
Colorectal cancer (CRC) largely affects older individuals; almost half of cases occur in
patients> 75 years old. The incidence increases with advancing age, doubling every 7 years …
patients> 75 years old. The incidence increases with advancing age, doubling every 7 years …