Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …
may increase the risk for heart failure development. This risk evolves from functional and …
An overview of murine high fat diet as a model for type 2 diabetes mellitus
A Heydemann - Journal of diabetes research, 2016 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …
increase. To help in combating the devastating array of phenotypes associated with T2DM a …
[HTML][HTML] The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats
S Steven, M Oelze, A Hanf, S Kröller-Schön, F Kashani… - Redox biology, 2017 - Elsevier
Hyperglycemia associated with inflammation and oxidative stress is a major cause of
vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a …
vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a …
Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome
DP Macfarlane, S Forbes… - Journal of …, 2008 - joe.bioscientifica.com
Estrogen affects proliferation and migration of different skin components, thus influencing
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …
Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics
A Arinno, C Maneechote, T Khuanjing, B Ongnok… - Biochemical …, 2021 - Elsevier
Doxorubicin (Dox) is widely used in chemotherapy regimens for several malignant
conditions. Unfortunately, cumulative and irreversible cardiotoxicity of Dox is the most …
conditions. Unfortunately, cumulative and irreversible cardiotoxicity of Dox is the most …
[HTML][HTML] Donepezil protects against doxorubicin-induced chemobrain in rats via attenuation of inflammation and oxidative stress without interfering with doxorubicin …
B Ongnok, T Khuanjing, T Chunchai, P Pantiya… - …, 2021 - Elsevier
Although doxorubicin (Dox) is an effective chemotherapy medication used extensively in the
treatment of breast cancer, it frequently causes debilitating neurological deficits known as …
treatment of breast cancer, it frequently causes debilitating neurological deficits known as …
Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury
P Tanajak, P Sa-Nguanmoo… - Journal of …, 2018 - joe.bioscientifica.com
Sodium-glucose cotransporter 2 inhibitor (SGLT2-i) effects on cardiac ischemia/reperfusion
(I/R) injury are unclear. Unlike SGLT2-i, dipeptidyl peptidase 4 inhibitors (DPP4-i) have …
(I/R) injury are unclear. Unlike SGLT2-i, dipeptidyl peptidase 4 inhibitors (DPP4-i) have …
[HTML][HTML] Targeting mitochondrial quality control for diabetic cardiomyopathy: therapeutic potential of hypoglycemic drugs
Y Zhou, W Suo, X Zhang, J Liang, W Zhao… - Biomedicine & …, 2023 - Elsevier
Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …
characterized by changes in myocardial structure and function, ultimately leading to heart …
Acetylcholinesterase inhibitor ameliorates doxorubicin-induced cardiotoxicity through reducing RIP1-mediated necroptosis
T Khuanjing, B Ongnok, C Maneechote… - Pharmacological …, 2021 - Elsevier
Doxorubicin is an effective chemotherapeutic drug, but causes cardiotoxicity which limits its
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …
Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals
C Marques, C Mega, A Gonçalves… - Mediators of …, 2014 - Wiley Online Library
This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP‐IV)
inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model …
inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model …