Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …

Hyperglycemia associated with inflammation and oxidative stress is a major cause of
vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a …

Estrogen affects proliferation and migration of different skin components, thus influencing
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …

Doxorubicin (Dox) is widely used in chemotherapy regimens for several malignant
conditions. Unfortunately, cumulative and irreversible cardiotoxicity of Dox is the most …

Although doxorubicin (Dox) is an effective chemotherapy medication used extensively in the
treatment of breast cancer, it frequently causes debilitating neurological deficits known as …

Sodium-glucose cotransporter 2 inhibitor (SGLT2-i) effects on cardiac ischemia/reperfusion
(I/R) injury are unclear. Unlike SGLT2-i, dipeptidyl peptidase 4 inhibitors (DPP4-i) have …

Diabetic cardiomyopathy is a chronic cardiovascular complication caused by diabetes that is
characterized by changes in myocardial structure and function, ultimately leading to heart …

Doxorubicin is an effective chemotherapeutic drug, but causes cardiotoxicity which limits its
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …

This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP‐IV)
inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model …