Generation of reactive oxygen species and related oxidants is an inevitable consequence of
life. Proteins are major targets for oxidation reactions, because of their rapid reaction rates …

Numerous rheumatologic autoimmune diseases, among which rheumatoid arthritis, are
chronic inflammatory diseases capable of inducing multiple cumulative articular and extra …

There are numerous extra-and intra-cellular processes involved in the production of reactive
oxygen species (ROS). Augmented ROS generation can cause the damage of biomolecules …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease whose pathogenic
mechanisms remain to be elucidated. The oxidative stress and antioxidants play an …

Patients with Chronic Inflammatory Rheumatic diseases (CIRD) are at increased risk of
cardiovascular disease (CVD), ascribed not only to classical risk factors, but also to the …

Autoimmune diseases, including psoriasis, systemic lupus erythematosus (SLE), and
rheumatic arthritis (RA), are caused by a combination of environmental and genetic factors …

Oxygen is used by eukaryotic cells for metabolic transformations and energy production in
mitochondria. Under physiological conditions, there is a constant endogenous production of …

Rheumatoid arthritis (RA) and celiac disease (CD) belong to the autoimmune disease
family. Despite being separate entities they share multiple aspects. Epidemiologically they …

Systemic autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and systemic
lupus erythematosus represent various autoimmune conditions identified by immune system …