The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …

Purpose. To investigate the efficacy of recombinant human collagen type I (RHC I) and
collagen‐like peptide (CLP) hydrogels as alternative carrier substrates for the cultivation of …

Transplantation of cultivated limbal epithelial transplantation has been proven to restore the
corneal surface in limbal stem cell deficiency (LSCD). Here we comparatively investigated …

The transparent corneal epithelium in the eye is maintained through the homeostasis
regulated by limbal stem cells (LSCs), while the nontransparent epidermis relies on …

Background Limbal stem cells (LSC) sustain the corneal integrity and homeostasis. LSC
deficiency (LSCD) leads to loss of corneal transparency and blindness. A clinical approach …

Tissue engineering is now preferred as a primary method utilizing cells in various therapies.
The transplantation of cells has been substantially promoted especially in some areas such …

Purpose: To develop autologous tissue-engineered conjunctival epithelial sheets to be used
as advanced therapy medicinal products for severe ocular surface disorders involving the …

Transplantation of human cultured limbal epithelial stem/progenitor cells (LESCs) has
demonstrated to restore the integrity and functionality of the corneal surface in about 76% of …

Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by
LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful …

The homeostasis of the transparent corneal epithelium in the eye is maintained by limbal
stem cells with proper cell fates. A potential disease mechanism underlying corneal opacity …