Melanocyte development provides an excellent model for studying more complex
developmental processes. Melanocytes have an apparently simple aetiology, differentiating …

The Hedgehog (Hh) signaling pathway is of central importance during embryo development
in metazoans and governs a diverse array of processes including cell proliferation …

Melanoma is a lethal melanocytic neoplasm. Unfortunately, the histological diagnosis can
be difficult at times. Distinguishing ambiguous melanocytic neoplasms that are benign nevi …

MicroRNAs are short regulatory RNAs that are able to post-transcriptionally modulate gene
expression and that have crucial roles in the control of physiological and pathological …

Congenital melanocytic nevi (CMN) are present at birth or arise during the first few weeks of
life. They are quite common, may have a heritable component, and can present with marked …

Human whole saliva is a bodily fluid that can be obtained easily by noninvasive techniques.
Specimens can be collected by the patient also at home in order to monitor health status and …

Tumors of nearly every origin activate the expression of genes normally restricted to
gametogenic cells. These genes encode proteins termed cancer/testis (CT) antigens, since …

Aims In this study, we have investigated the effects of apigenin-7-glucoside, genkwanin and
naringenin, on mouse melanoma B16F10 cell proliferation. Influence of these natural …

Epidermal melanocytes play an important role in protecting the skin from UV rays, and their
functional impairment results in pigment disorders. Additionally, melanomas are considered …

Endothelin (Edn) signaling via the G‐coupled, Edn receptor type B (Ednrb) is essential for
the development of melanocytes from the neural crest (NC) and has been associated with …