Linking the amyloid, tau, and mitochondrial hypotheses of Alzheimer's disease and identifying promising drug targets
Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
Therapeutic strategies aimed at improving neuroplasticity in Alzheimer disease
MF Colavitta, FJ Barrantes - Pharmaceutics, 2023 - mdpi.com
Alzheimer disease (AD) is the most prevalent form of dementia among elderly people.
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
Owing to its varied and multicausal etiopathology, intervention strategies have been highly …
Novel therapeutic approaches to target neurodegeneration
AG de la Fuente, S Pelucchi, J Mertens… - British Journal of …, 2023 - Wiley Online Library
Ageing is the main risk factor common to most primary neurodegenerative disorders. Indeed,
age‐related brain alterations have been long considered to predispose to …
age‐related brain alterations have been long considered to predispose to …
Light, water, and melatonin: the synergistic regulation of phase separation in dementia
The swift rise in acceptance of molecular principles defining phase separation by a broad
array of scientific disciplines is shadowed by increasing discoveries linking phase …
array of scientific disciplines is shadowed by increasing discoveries linking phase …
A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia
A Crestini, E Carbone, R Rivabene, A Ancidoni, P Rosa… - Cells, 2024 - mdpi.com
Acetylcholine signaling is attenuated in early Alzheimer's disease (AD) and other dementias.
A significant reduction in the expression of nicotinic acetylcholine receptors (nAChRs) in the …
A significant reduction in the expression of nicotinic acetylcholine receptors (nAChRs) in the …
Mapping new pharmacological interventions for cognitive function in Alzheimer's disease: a systematic review of randomized clinical trials
I Xu Lou, J Chen, K Ali, AL Shaikh… - Frontiers in Pharmacology, 2023 - frontiersin.org
Background and Objective: Alzheimer's disease (AD) is a progressive neurodegenerative
disorder, that is, characterized by cognitive decline. To date, there are no effective …
disorder, that is, characterized by cognitive decline. To date, there are no effective …
Saponin components in Polygala tenuifolia as potential candidate drugs for treating dementia
S Li, Z Hou, T Ye, X Song, X Hu, J Chen - Frontiers in Pharmacology, 2024 - frontiersin.org
Objective This study aims to elucidate the intervention effects of saponin components from
Polygala tenuifolia Willd (Polygalaceae) on dementia, providing experimental evidence and …
Polygala tenuifolia Willd (Polygalaceae) on dementia, providing experimental evidence and …
[PDF][PDF] INVESTIGATION OF MODIFIABLE SOCIAL AND BEHAVIOURAL RISK FACTORS OF COGNITIVE DECLINE AND DEMENTIA
M KLEE - 2024 - orbilu.uni.lu
Dementia is recognised as a public health priority, affecting not only people living with the
syndrome but also formal and informal carers as well as society at large. The growing …
syndrome but also formal and informal carers as well as society at large. The growing …
Novel therapeutic approaches to target neurodegeneration
Ageing is the main risk factor common to most primary neurodegenerative disorders. Indeed,
age-related brain alterations have been long considered to predispose to …
age-related brain alterations have been long considered to predispose to …