Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern.
Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is …

The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism—
circadian rhythmicity—to anticipate the daily changes caused by this rotation. The molecular …

There is robust evidence of an association between insomnia, anxiety, and depression in
adolescence. The aim of this review is to describe and synthesize potential mechanisms …

Hypothalamic syndrome (HS) is a rare disorder caused by disease-related and/or treatment-
related injury to the hypothalamus, most commonly associated with rare, non-cancerous …

A bíblia azul da farmacologia–assim tem sido mundialmente chamado este clássico
acadêmico desde o lançamento de sua 1ª edição, em 1941. A nova edição de Goodman & …

The prevention of perioperative neurocognitive disorders is a priority for patients, families,
clinicians, and researchers. Given the multiple risk factors present throughout the …

Pro-inflammatory systemic conditions that can cause neuroinflammation and subsequent
alterations in brain regions involved in emotional regulation have been suggested as an …

These practice parameters are an update of the previously-published recommendations
regarding the indications for polysomnography and related procedures in the diagnosis of …

Thermal environment in bedrooms is still a largely neglected topic in thermal comfort
research, although a thermal comfortable environment is important for sleep maintenance …

Sleep disorders are common in the general population and even more so in clinical practice,
yet are relatively poorly understood by doctors and other health care practitioners. These …