Synthesis and Development of N-2,5-Dimethylphenylthioureido Acid Derivatives as Scaffolds for New Antimicrobial Candidates Targeting Multidrug-Resistant Gram …

P Kavaliauskas, B Grybaitė, R Vaickelionienė… - Antibiotics, 2023 - mdpi.com
The growing antimicrobial resistance to last-line antimicrobials among Gram-positive
pathogens remains a major healthcare emergency worldwide. Therefore, the search for new …

Synthesis and antimicrobial activity of N-(4-chlorophenyl)-β-alanine derivatives with an azole moiety

K Anusevičius, I Jonuškienė, V Mickevičius - Monatshefte für Chemie …, 2013 - Springer
Abstract N-(4-Chlorophenyl)-β-alanine was shown to be a useful synthetic intermediate for
synthesis of azole heterocycles. Their structure was characterized by IR, mass, and NMR …

[PDF][PDF] Synthesis and Antibacterial Activity of Novel N-Carboxyalkyl-N-phenyl-2-aminothia (oxa) zole Derivatives

R Vaickelioniene, K Mickeviciene… - …, 2015 - triggered.edina.clockss.org
N-Phenyl-N-thiocarbamoyl-α-and β-methyl-β-alanines were converted into a series of 1, 3-
thiazole derivatives by treatment with chloroacetaldehyde and haloketones. The reaction of …

Synthesis and antibacterial and antifungal activity of N-(4-fluorophenyl)-N-carboxyethylaminothiazole derivatives

R Vaickelionienė, V Mickevičius, G Vaickelionis… - Arkivoc, 2015 - epubl.ktu.edu
Abstract [eng] A series of novel N-(4-fluorophenyl)-N-carboxyethylaminothiazoles and
thiazolones with aliphatic, aromatic and heterocyclic substituents were obtained in good to …

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R Vaickelioniene, K Mickeviciene, K Anusevicius… - triggered.stanford.clockss.org
Substituted 1-(4-fluoro-and 4-chlorophenyl) pyrrolidin-2-ones containing azole, oxadiazole,
triazole, and triazine fragments have been synthesized, and the characterization of the …

[PDF][PDF] 3-[(2, 5-dimetilfenil)(4-aril-1, 3-tiazol-2-il) amino] propano rūgšties darinių sintezė ir jų antibakterinis, antioksidacinis aktyvumo tyrimas

A Kriaučiūnaitė - 2019 - epubl.ktu.edu
Abstract [eng] Recently, great attention of scientists has been paid to the synthesis of new
biologically active compounds that could be effective in treating bacterial infections. In this …

Synthesis and investigation of functionalized fluoro-containing azoles and azines

R Vaickelionienė - 2015 - epubl.ktu.edu
Abstract [eng] The incorporation of fluorine into organic molecules can dramatically alter
their reactivity, chemical and biological properties, and physiological activity. The main aim …

Fluoro turinčių funkcionalizuotų azolų ir azinų sintezė bei tyrimas

R Vaickelionienė - 2015 - epubl.ktu.edu
Abstract [eng] The incorporation of fluorine into organic molecules can dramatically alter
their reactivity, chemical and biological properties, and physiological activity. The main aim …