Recent advances of liquid biopsy: Interdisciplinary strategies toward clinical decision‐making
Liquid biopsy has emerged as a promising avenue for non‐invasive and rapid retrieval of
pathological information from patient body fluids. Over the years, liquid biopsy has garnered …
pathological information from patient body fluids. Over the years, liquid biopsy has garnered …
Hydraulic–electric analogy for design and operation of microfluidic systems
Microfluidic systems have been investigated as practical tools in the fields of biomedical
engineering, analytical chemistry, materials science, and biological research. Yet the …
engineering, analytical chemistry, materials science, and biological research. Yet the …
Direct isolation of small extracellular vesicles from human blood using viscoelastic microfluidics
Small extracellular vesicles (sEVs;< 200 nm) that contain lipids, nucleic acids, and proteins
are considered promising biomarkers for a wide variety of diseases. Conventional methods …
are considered promising biomarkers for a wide variety of diseases. Conventional methods …
EVs‐on‐a‐Bubble: Self‐Aggregated Click Bubbles Streamline Isolation and Amplified Profiling of Circulating Extracellular Vesicles
B Wei, Y Xiang, X Qin, Y Yang, H Lu… - Advanced Functional …, 2024 - Wiley Online Library
Tumor‐derived circulating extracellular vesicles (EVs) provide a non‐invasive solution for
cancer diagnostics, but hampered by challenges in EVs isolation and profiling. Herein, this …
cancer diagnostics, but hampered by challenges in EVs isolation and profiling. Herein, this …
Advanced Nanoencapsulation-Enabled Ultrasensitive Analysis: Unraveling Tumor Extracellular Vesicle Subpopulations for Differential Diagnosis of Hepatocellular …
X Li, Y Liu, Y Fan, G Tian, B Shen, S Zhang, X Fu… - ACS …, 2024 - ACS Publications
Tumor-derived extracellular vesicles (tEVs) hold immense promise as potential biomarkers
for the precise diagnosis of hepatocellular carcinoma (HCC). However, their clinical …
for the precise diagnosis of hepatocellular carcinoma (HCC). However, their clinical …
High-Throughput Microfluidic Extraction of Platelet-free Plasma for MicroRNA and Extracellular Vesicle Analysis
SY Leong, WW Lok, KY Goh, HB Ong, HM Tay, C Su… - ACS …, 2024 - ACS Publications
Cell-free RNAs and extracellular vesicles (EVs) are valuable biomarkers in liquid biopsies,
but they are prone to preanalytical variabilities such as nonstandardized centrifugation or ex …
but they are prone to preanalytical variabilities such as nonstandardized centrifugation or ex …
Emerging Microfluidic Tools for Simultaneous Exosomes and Cargo Biosensing in Liquid Biopsy: New Integrated Miniaturized FFF-Assisted Approach for Colon …
V Marassi, S Giordani, A Placci, A Punzo, C Caliceti… - Sensors, 2023 - mdpi.com
The early-stage diagnosis of cancer is a crucial clinical need. The inadequacies of surgery
tissue biopsy have prompted a transition to a less invasive profiling of molecular biomarkers …
tissue biopsy have prompted a transition to a less invasive profiling of molecular biomarkers …
Thermophoretic glycan profiling of extracellular vesicles for triple-negative breast cancer management
Triple-negative breast cancer (TNBC) is a highly metastatic and heterogeneous type of
breast cancer with poor outcomes. Precise, non-invasive methods for diagnosis, monitoring …
breast cancer with poor outcomes. Precise, non-invasive methods for diagnosis, monitoring …
Microfluidic Device-Based In Vivo Detection of PD-L1-Positive Small Extracellular Vesicles and Its Application for Tumor Monitoring
XZ Cong, J Feng, HJ Zhang, LZ Zhang, TY Lin… - Analytical …, 2024 - ACS Publications
Liquid biopsy is of great significance in tumor early diagnosis and treatment stratification. PD-
L1-positive small extracellular vesicles (PD-L1+ sEVs) are closely related to tumor growth …
L1-positive small extracellular vesicles (PD-L1+ sEVs) are closely related to tumor growth …
Tumor-derived extracellular vesicle drug delivery system for chemo-photothermal-immune combination cancer treatment
Y Bi, J Chen, Q Li, Y Li, L Zhang, L Zhida, F Yuan… - Iscience, 2024 - cell.com
Tumor extracellular vesicles (EVs) demonstrate considerable promise for medication
delivery and tumor targeting owing to their natural long-term blood circulation and tissue …
delivery and tumor targeting owing to their natural long-term blood circulation and tissue …