Proteins are the primary effectors of function in biology, and thus, complete knowledge of
their structure and properties is fundamental to deciphering function in basic and …

The quest for realizing and manipulating ever smaller man-made movable structures and
dynamical machines has spurred tremendous endeavors, led to important discoveries, and …

Nanomechanics has brought mesoscopic physics into the world of vibrations. Because
nanomechanical systems are small, fluctuations are significant, the vibrations already …

Single-cell profiling methods have had a profound impact on the understanding of cellular
heterogeneity. While genomes and transcriptomes can be explored at the single-cell level …

We demonstrate single-particle charge detection mass spectrometry on an Orbitrap for the
analysis of megadalton biomolecular assemblies. We establish that the signal amplitudes of …

Low-frequency vibration modes of biological particles, such as proteins, viruses and
bacteria, involve coherent collective vibrations at frequencies in the terahertz and gigahertz …

MEMS/NEMS resonators are widely studied in biological detection, physical sensing, and
quantum coupling. This paper reviews the latest research progress of MEMS/NEMS …

Nanomechanical mass spectrometry has proven to be well suited for the analysis of high
mass species such as viruses. Still, the use of one-dimensional devices such as vibrating …

Here we review recent developments in mass spectrometry that have enabled its growing
contribution to the field of structural virology. Evidently, there is a strong renewed general …

The characterisation of individual nanoparticles by single particle ICP-MS (SP-ICP-MS) has
paved the way for the analysis of smallest biological systems. This study suggests to …