The urothelium, which lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, not only forms a high-resistance barrier to ion, solute and water flux, and …

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

The lower urinary tract constitutes a functional unit controlled by a complex interplay
between the central and peripheral nervous systems and local regulatory factors. In the …

The storage and periodic elimination of urine, termed micturition, requires a complex neural
control system to coordinate the activities of the urinary bladder, urethra, and urethral …

Storage and periodic expulsion of urine is regulated by a neural control system in the brain
and spinal cord that coordinates the reciprocal activity of two functional units in the lower …

Summary 1 Muscarinic M1–M5 receptors mediate the metabotropic actions of acetylcholine
in the nervous system. A growing body of data indicate they also mediate autocrine functions …

1. The parasympathetic nervous system is responsible for maintaining normal bladder
function, contracting the bladder smooth muscle (detrusor) and relaxing the bladder outlet …

This review deals with individual components regulating the neural control of the urinary
bladder. This article will focus on factors and processes involved in the two modes of …

We investigated muscarinic receptors in the detrusor and mucosa of the human bladder
body. Radioligand-binding studies with [3 H] QNB were conducted using specimens …

Lower urinary tract symptoms (LUTS) can be categorized as storage, voiding, and
postmicturition symptoms. Although often associated with benign prostatic hyperplasia …