Current epidemiology in hepatocellular carcinoma

P Konyn, A Ahmed, D Kim - Expert review of gastroenterology & …, 2021 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third-
leading cause of cancer-related mortality in the world. Areas covered This review will …

The evolving epidemiology of hepatocellular carcinoma: a global perspective

MC Wallace, D Preen, GP Jeffrey… - Expert review of …, 2015 - Taylor & Francis
Primary liver cancer, the majority of which are hepatocellular carcinomas, is now the second
leading cause of cancer death worldwide. Hepatocellular carcinoma is a unique cancer that …

Origin, HDV genotype and persistent viremia determine outcome and treatment response in patients with chronic hepatitis delta

D Roulot, S Brichler, R Layese, Z BenAbdesselam… - Journal of …, 2020 - Elsevier
Background & Aims HDV infection causes severe chronic liver disease in individuals
infected with HBV. However, the factors associated with poor prognosis are largely …

The hepatitis delta virus: Replication and pathogenesis

C Sureau, F Negro - Journal of hepatology, 2016 - Elsevier
Hepatitis delta virus (HDV) is a defective virus and a satellite of the hepatitis B virus (HBV).
Its RNA genome is unique among animal viruses, but it shares common features with some …

Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial

C Koh, L Canini, H Dahari, X Zhao… - The Lancet Infectious …, 2015 - thelancet.com
Background Therapies for chronic hepatitis delta virus (HDV) infection are unsatisfactory.
Prenylation is essential for HDV and inhibition abrogates HDV production in experimental …

Molecular mechanisms of the preventable causes of cancer in the United States

EA Golemis, P Scheet, TN Beck… - Genes & …, 2018 - genesdev.cshlp.org
Abstract Annually, there are 1.6 million new cases of cancer and nearly 600,000 cancer
deaths in the United States alone. The public health burden associated with these numbers …

Prevalence of hepatitis B and hepatitis D virus infections in the United States, 2011–2016

EU Patel, CL Thio, D Boon, DL Thomas… - Clinical Infectious …, 2019 - academic.oup.com
Among adults in the 2011-2016 National Health and Nutrition Examination Survey
(NHANES), the estimated prevalence of hepatitis B surface antigen (HBsAg) was 0.36 …

[HTML][HTML] A review on hepatitis D: From virology to new therapies

N Mentha, S Clément, F Negro, D Alfaiate - Journal of advanced research, 2019 - Elsevier
Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to
complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating …

[PDF][PDF] Long‐term study of hepatitis delta virus infection at secondary care centers: the impact of viremia on liver‐related outcomes

H Kamal, G Westman, K Falconer, AS Duberg… - …, 2020 - Wiley Online Library
Background and Aims Hepatitis delta virus (HDV) infection is associated with fast
progression to liver cirrhosis and liver complications. Previous studies have, however, been …

Host and viral genetic variation in HBV-related hepatocellular carcinoma

P An, J Xu, Y Yu, CA Winkler - Frontiers in genetics, 2018 - frontiersin.org
Hepatocellular carcinoma (HCC) is the fifth most common cancer in men and the second
leading cause of cancer deaths globally. The high prevalence of HCC is due in part to the …