Proteoglycan sequence

L Li, M Ly, RJ Linhardt - Molecular BioSystems, 2012 - pubs.rsc.org
Proteoglycans (PGs) are among the most structurally complex biomacromolecules in nature.
They are present in all animal cells and frequently exert their critical biological functions …

More than matrix: the multifaceted role of decorin in cancer

DDS Feugaing, M Götte, M Viola - European journal of cell biology, 2013 - Elsevier
The small leucine-rich proteoglycan, decorin, has incrementally been shown to be a
powerful inhibitor of growth in a wide variety of tumour cells, an effect specifically mediated …

The proteoglycan bikunin has a defined sequence

M Ly, FE Leach III, TN Laremore, T Toida… - Nature chemical …, 2011 - nature.com
Proteoglycans are complex glycoconjugates that regulate critical biological pathways in all
higher organisms. Bikunin, the simplest proteoglycan, with a single glycosaminoglycan …

Sequencing the dermatan sulfate chain of decorin

Y Yu, J Duan, FE Leach III, T Toida… - Journal of the …, 2017 - ACS Publications
Glycomics represents one of the last frontiers and most challenging in omic analysis.
Glycosylation occurs in the endoplasmic reticulum and the Golgi organelle and its control is …

Disaccharide analysis of glycosaminoglycans using hydrophilic interaction chromatography and mass spectrometry

VL Gill, U Aich, S Rao, C Pohl, J Zaia - Analytical chemistry, 2013 - ACS Publications
Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) glycosaminoglycans
(GAGs) participate in many important biological processes. Quantitative disaccharide …

Composition of glycosaminoglycans in elasmobranchs including several deep-sea sharks: identification of chondroitin/dermatan sulfate from the dried fins of Isurus …

K Higashi, Y Takeuchi, A Mukuno, H Tomitori, M Miya… - Plos one, 2015 - journals.plos.org
Shark fin, used as a food, is a rich source of glycosaminoglyans (GAGs), acidic
polysaccharides having important biological activities, suggesting their nutraceutical and …

Harnessing chondroitin sulphate in composite scaffolds to direct progenitor and stem cell function for tissue repair

BL Farrugia, MS Lord, JM Whitelock, J Melrose - Biomaterials science, 2018 - pubs.rsc.org
The development of bioscaffolds that incorporate chondroitin sulphate (CS) and their
applications with progenitor and stem cells in cartilage, bone, cornea, skin, and neural repair …

Mapping the human chondroitin sulfate glycoproteome reveals an unexpected correlation between glycan sulfation and attachment site characteristics

F Noborn, J Nilsson, C Sihlbom, M Nikpour… - Molecular & Cellular …, 2023 - ASBMB
Chondroitin sulfate proteoglycans (CSPGs) control key events in human health and disease
and are composed of chondroitin sulfate (CS) polysaccharide (s) attached to different core …

Isolation of bovine corneal keratan sulfate and its growth factor and morphogen binding

A Weyers, B Yang, K Solakyildirim, V Yee, L Li… - The FEBS …, 2013 - Wiley Online Library
Keratan sulfate (KS) is an important glycosaminoglycan that is found in cartilage,
reproductive tissues, and neural tissues. Corneal KS glycosaminoglycan is found N‐linked …

Neoproteoglycans in tissue engineering

A Weyers, RJ Linhardt - The FEBS journal, 2013 - Wiley Online Library
Proteoglycans, comprised of a core protein to which glycosaminoglycan chains are
covalently linked, are an important structural and functional family of macromolecules found …