The emerging science of interoception: sensing, integrating, interpreting, and regulating signals within the self

WG Chen, D Schloesser, AM Arensdorf… - Trends in …, 2021 - cell.com
Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

Neural circuits of interoception

GG Berntson, SS Khalsa - Trends in neurosciences, 2021 - cell.com
The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …

[HTML][HTML] A multidimensional coding architecture of the vagal interoceptive system

Q Zhao, CD Yu, R Wang, QJ Xu, R Dai Pra, L Zhang… - Nature, 2022 - nature.com
Interoception, the ability to timely and precisely sense changes inside the body, is critical for
survival,,–. Vagal sensory neurons (VSNs) form an important body-to-brain connection …

A new science of emotion: implications for functional neurological disorder

J Jungilligens, S Paredes-Echeverri, S Popkirov… - Brain, 2022 - academic.oup.com
Functional neurological disorder reflects impairments in brain networks leading to
distressing motor, sensory and/or cognitive symptoms that demonstrate positive clinical …

[HTML][HTML] Atypical interoception as a common risk factor for psychopathology: A review

R Brewer, J Murphy, G Bird - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The inadequacy of a categorial approach to mental health diagnosis is now well-recognised,
with many authors, diagnostic manuals and funding bodies advocating a dimensional, trans …

Computational models of interoception and body regulation

FH Petzschner, SN Garfinkel, MP Paulus, C Koch… - Trends in …, 2021 - cell.com
To survive, organisms must effectively respond to the challenge of maintaining their
physiological integrity in the face of an ever-changing environment. Preserving this …

Interventions and manipulations of interoception

HY Weng, JL Feldman, L Leggio, V Napadow… - Trends in …, 2021 - cell.com
Interoceptive pathways may be manipulated at various levels to develop interventions to
improve symptoms in a range of disorders. Primarily through the lens of the respiratory …

Allostasis, action, and affect in depression: insights from the theory of constructed emotion

C Shaffer, C Westlin, KS Quigley… - Annual review of …, 2022 - annualreviews.org
The theory of constructed emotion is a systems neuroscience approach to understanding the
nature of emotion. It is also a general theoretical framework to guide hypothesis generation …

Cognition, emotion, and the central autonomic network

L Quadt, H Critchley, Y Nagai - Autonomic Neuroscience, 2022 - Elsevier
The demands of both mental and physical activity are integrated with the dynamic control of
internal bodily states. The set of neural interactions that supports autonomic regulation …

A predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia

JA Migeot, CA Duran-Aniotz, CM Signorelli… - Trends in …, 2022 - cell.com
Recent allostatic–interoceptive explanations using predictive coding models propose that
efficient regulation of the body's internal milieu is necessary to correctly anticipate …