Cadmium and its neurotoxic effects

B Wang, Y Du - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Cadmium (Cd) is a heavy metal that has received considerable concern environmentally
and occupationally. Cd has a long biological half‐life mainly due to its low rate of excretion …

Developmental neurotoxicity of succeeding generations of insecticides

Y Abreu-Villaça, ED Levin - Environment international, 2017 - Elsevier
Insecticides are by design toxic. They must be toxic to effectively kill target species of insects.
Unfortunately, they also have off-target toxic effects that can harm other species, including …

Environmental and health effects of pesticide residues

S Ali, MI Ullah, A Sajjad, Q Shakeel… - … Agriculture Reviews 48 …, 2021 - Springer
Now a days, agroecosystem is largely dependent on pesticides to meet the ever-increasing
demand of food and fiber. Tons of synthetic pesticides are deposited to increase the yield …

[HTML][HTML] Recommendation on test readiness criteria for new approach methods (NAM) in toxicology: exemplified for developmental neurotoxicity (DNT)

A Bal-Price, HT Hogberg, KM Crofton, M Daneshian… - Altex, 2018 - ncbi.nlm.nih.gov
Multiple non-animal-based test methods have never been formally validated. In order to use
such new approach methods (NAMs) in a regulatory context, criteria to define their …

[HTML][HTML] Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their …

M Aschner, S Ceccatelli, M Daneshian, E Fritsche… - Altex, 2017 - ncbi.nlm.nih.gov
There is a paucity of information concerning the developmental neurotoxicity (DNT) hazard
posed by industrial and environmental chemicals. New testing approaches will most likely …

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities

BZ Schmidt, M Lehmann, S Gutbier, E Nembo… - Archives of …, 2017 - Springer
Neurotoxicity and developmental neurotoxicity are important issues of chemical hazard
assessment. Since the interpretation of animal data and their extrapolation to man is …

Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier

A Martinez, AJ Al-Ahmad - Toxicology letters, 2019 - Elsevier
Glyphosate is a pesticide used for occupational and non-occupational purposes. Because
glyphosate targets a metabolic pathway absent in animals, it is considered safe for humans …

Exposure to a glyphosate-based herbicide during pregnancy and lactation induces neurobehavioral alterations in rat offspring

CE Gallegos, M Bartos, C Bras, F Gumilar… - Neurotoxicology, 2016 - Elsevier
The impact of sub-lethal doses of herbicides on human health and the environment is a
matter of controversy. Due to the fact that evidence particularly of the effects of glyphosate on …

OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes

E Fritsche, KM Crofton, AF Hernandez… - 2017 - kops.uni-konstanz.de
The last talks, given by academic researchers, were geared to set the stage for breakout
group discussions. They reviewed the scientific principles of alternative DNT methods to test …

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing

A Vassallo, M Chiappalone, RDC Lopes, B Scelfo… - Neurotoxicology, 2017 - Elsevier
There is a need for methods to screen and prioritize chemicals for potential hazard,
including neurotoxicity. Microelectrode array (MEA) systems enable simultaneous …