Simple Summary Researchers have shown that tumor biomarkers and increased nerve
density are important clinical tools for determining cancer prognosis and developing …

This review provides an overview of the application of artificial intelligence (AI) in radiation
therapy (RT) from a radiation oncologist's perspective. Over the years, advances in …

Perineural invasion (PNI) is the process through which tumors invade and interact with
nerves. The dynamic changes in the nerves caused by PNI may induce disturbing …

The rationale behind the integration of PET and MR imaging lies in the complementary
strengths of each modality. PET provides metabolic information using radiotracers, whereas …

The purpose of this study was to review the diagnostic accuracy of MRI in detecting
perineural spreading (PNS) of head and neck tumors using histopathological or surgical …

Abstract Background/Objectives: Cutaneous squamous cell carcinoma (cSCC) is the second
most common skin cancer, with a lifetime risk of 14–20% that is rising every year. Although …

Head and neck cancer management requires multidisciplinary approach in which radical
surgery with or without flap reconstructions and neck dissection, along with radiotherapy …

Methods A review of literature using PubMED was performed for studies reporting the
management of LAOCSCC. Based on the reviewed literature and opinions of experts in the …

Background Perineural spread (PNS) is associated with a poor prognosis in cutaneous
squamous cell carcinoma of the head and neck (cSCCHN). Hence, investigating facilitators …

Perineural tumor spread (PNS) of head and neck cancer was first described in the 1800s. 1,
2 However, it was not until 1963 when Ballantyne and colleagues published 80 cases …