The function of gut microbiota in immune-related neurological disorders: A review
P Sittipo, J Choi, S Lee, YK Lee - Journal of Neuroinflammation, 2022 - Springer
This review provides an overview of the importance of microbiota in the regulation of gut–
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …
Microbiota metabolites in health and disease
JL McCarville, GY Chen, VD Cuevas… - Annual review of …, 2020 - annualreviews.org
Metabolism is one of the strongest drivers of interkingdom interactions—including those
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …
B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
Small, soluble metabolites not only are essential intermediates in intracellular biochemical
processes, but can also influence neighbouring cells when released into the extracellular …
processes, but can also influence neighbouring cells when released into the extracellular …
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
D Huang, Y Wang, JW Thompson, T Yin… - Nature cell …, 2022 - nature.com
Many cancers have an unusual dependence on glutamine. However, most previous studies
have focused on the contribution of glutamine to metabolic building blocks and the energy …
have focused on the contribution of glutamine to metabolic building blocks and the energy …
[HTML][HTML] GABA-receptive microglia selectively sculpt developing inhibitory circuits
Microglia, the resident immune cells of the brain, have emerged as crucial regulators of
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour
Immune dysfunction is commonly associated with several neurological and mental
disorders. Although the mechanisms by which peripheral immunity may influence neuronal …
disorders. Although the mechanisms by which peripheral immunity may influence neuronal …
Cytokine targets in the brain: impact on neurotransmitters and neurocircuits
Increasing attention has been paid to the role of inflammation in a host of illnesses including
neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory …
neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory …
[HTML][HTML] Neurosteroids as regulators of neuroinflammation
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …
injury. However, neuroinflammation, especially if chronic, may also drive …
Probiotics function mechanistically as delivery vehicles for neuroactive compounds: microbial endocrinology in the design and use of probiotics
M Lyte - Bioessays, 2011 - Wiley Online Library
I hypothesize here that the ability of probiotics to synthesize neuroactive compounds
provides a unifying microbial endocrinology‐based mechanism to explain the hitherto …
provides a unifying microbial endocrinology‐based mechanism to explain the hitherto …
Ion channels and transporters in lymphocyte function and immunity
S Feske, EY Skolnik, M Prakriya - Nature Reviews Immunology, 2012 - nature.com
Lymphocyte function is regulated by a network of ion channels and transporters in the
plasma membrane of B and T cells. These proteins modulate the cytoplasmic concentrations …
plasma membrane of B and T cells. These proteins modulate the cytoplasmic concentrations …