Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of
infectious diseases. Development of new classes of antibiotics has slowed in recent years …

Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Antimicrobial pharmaceuticals are classified as emergent micropollutants of concern,
implying that even at low concentrations, long-term exposure to the environment can have …

Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in
Western medicine. This stems from the rise in frequency of multi-drug-resistant bacterial …

For a bacteriophage to be useful for phage therapy it must be both isolated from the
environment and shown to have certain characteristics beyond just killing strains of the …

Intestinal microbiota are involved in the pathogenesis of Crohn's disease, ulcerative colitis,
and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses …

Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted
towards alternative therapies for treating infections. Although several alternatives already …