In recent years, the global public health community has increasingly recognized the
importance of antimicrobial stewardship (AMS) in the fight to improve outcomes, decrease …

In light of the frequency, morbidity and mortality associated with influenza-associated
aspergillosis in the ICU, a high awareness of the diagnosis and prompt initiation of …

Recently, recurrent neural networks (RNNs) have been applied in predicting disease onset
risks with Electronic Health Record (EHR) data. While these models demonstrated …

Objectives: Sepsis-3 defines organ dysfunction as an increase in the Sequential Organ
Failure Assessment score by greater than or equal to 2 points. However, some Sequential …

Isavuconazole is the newest of the clinically available advanced generation triazole
antifungals and is active against a variety of yeasts, molds, and dimorphic fungi. Its current …

Patients undergoing treatment with immunosuppressant drugs following solid organ or
hematopoietic stem cell transplantation are at particular risk for development of serious …

Background Lung transplant recipients commonly develop invasive fungal infections (IFIs),
but the most effective strategies to prevent IFIs following lung transplantation are not known …

Therapeutic drug monitoring (TDM) may be required to achieve optimal clinical outcomes in
the setting of significant pharmacokinetic variability, a situation that applies to a number of …

Objectives The objectives of this study were to explore inter-study heterogeneity in the
pharmacokinetics (PK) of orally administered rifampicin, to derive summary estimates of …

In the recent past, prevalence of life threatening fungal diseases have increased rapidly in
immune-compromised cases such as acquired immunodeficiency syndrome (AIDS), cancer …