Circular RNA in renal diseases

J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Angiotensin-converting enzyme inhibitors from plants: A review of their diversity, modes of action, prospects, and concerns in the management of diabetes-centric …

R Chakraborty, S Roy - Journal of Integrative Medicine, 2021 - Elsevier
Angiotensin-converting enzyme (ACE) inhibitors are antihypertensive medications often
used in the treatment of diabetes-related complications. Synthetic ACE inhibitors are known …

Platycodin D regulates high glucose-induced ferroptosis of HK-2 cells through glutathione peroxidase 4 (GPX4)

J Huang, G Chen, J Wang, S Liu, J Su - Bioengineered, 2022 - Taylor & Francis
Diabetic nephropathy (DN) is associated with inflammation. Platycodin D (PD) demonstrates
anti-inflammatory activity. However, whether PD affects DN remains to be explored. Here …

The pathogenic role of intestinal flora metabolites in diabetic nephropathy

E Tian, F Wang, L Zhao, Y Sun, J Yang - Frontiers in Physiology, 2023 - frontiersin.org
With the increasing incidence of diabetes, diabetic kidney disease has become a major
cause of chronic kidney disease. The role of the gut microbiota in diabetes and its related …

Roles of gut microbial metabolites in diabetic kidney disease

Q Fang, N Liu, B Zheng, F Guo, X Zeng… - Frontiers in …, 2021 - frontiersin.org
Diabetes is a highly prevalent metabolic disease that has emerged as a global challenge
due to its increasing prevalence and lack of sustainable treatment. Diabetic kidney disease …

Emerging trends in nano-based antidiabetic therapeutics: a path to effective diabetes management

R Sharma, SJ Borah, S Kumar, A Gupta, V Kumari… - Materials …, 2023 - pubs.rsc.org
Diabetes mellitus is characterized by altered blood sugar homeostasis. Diabetic mortality
rates are escalating in developed countries by the day. Currently, no effective treatment and …

The role and mechanism of gut microbiota-derived short-chain fatty in the prevention and treatment of diabetic kidney disease

P Tao, J Ji, Q Wang, M Cui, M Cao, Y Xu - Frontiers in Immunology, 2022 - frontiersin.org
Diabetic kidney disease (DKD), an emerging global health issue, is one of the most severe
microvascular complications derived from diabetes and a primary pathology contributing to …

The extract of Polygala fallax Hemsl. slows the progression of diabetic nephropathy by targeting TLR4 anti-inflammation and MMP-2/9-mediated anti-fibrosis in vitro

M Wang, X Liu, Z Wang, Q Xu - Phytomedicine, 2022 - Elsevier
Abstract Background Polygala fallax Hemsl. is a plant that is commonly used as a folk
medicine by Guangxi ethnic minorities, and it is also widely used in the clinical treatment of …

[HTML][HTML] Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression

J Ji, P Tao, Q Wang, M Cui, M Cao, Y Xu - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) poses a threat to people's health. The current treatments only
provide partial relief of symptoms. Therefore, seeking a promising therapeutic medication for …

Non-coding RNAs as biomarkers and therapeutic targets for diabetic kidney disease

YY Gu, FH Lu, XR Huang, L Zhang, W Mao… - Frontiers in …, 2021 - frontiersin.org
Diabetic kidney disease (DKD) is the most common diabetic complication and is a leading
cause of end-stage kidney disease. Increasing evidence shows that DKD is regulated not …