[HTML][HTML] Lysyl oxidases: emerging biomarkers and therapeutic targets for various diseases
Therapeutic targeting of extracellular proteins has attracted huge attention in treating human
diseases. The lysyl oxidases (LOXs) are a family of secreted copper-dependent enzymes …
diseases. The lysyl oxidases (LOXs) are a family of secreted copper-dependent enzymes …
What is the relevance of bioinformatics to pharmacology?
PA Whittaker - Trends in Pharmacological Sciences, 2003 - cell.com
Although bioinformatics achieved prominence because of its central role in genome data
storage, management and analysis, its focus has shifted as the life sciences exploit these …
storage, management and analysis, its focus has shifted as the life sciences exploit these …
Inflammasomes are differentially expressed in cardiovascular and other tissues
To determine the expression of components in Toll-like receptors (TLRs)/Nod-like receptors
(NLRs)/inflammasome/caspase-1/interleukin (IL-1)-β pathway, we examined the expression …
(NLRs)/inflammasome/caspase-1/interleukin (IL-1)-β pathway, we examined the expression …
[HTML][HTML] In silico identification and expression of SLC30 family genes: An expressed sequence tag data mining strategy for the characterization of zinc transporters' …
M Seve, F Chimienti, S Devergnas, A Favier - BMC genomics, 2004 - Springer
Background Intracellular zinc concentration and localization are strictly regulated by two
main protein components, metallothioneins and membrane transporters. In mammalian …
main protein components, metallothioneins and membrane transporters. In mammalian …
[HTML][HTML] Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis
PG Park, SJ Jo, MJ Kim, HJ Kim, JH Lee, CK Park… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most dangerous types of malignant tumors, and
cancer metastasis is a major factor in the failure of CRC therapy. Recently, LOXL2 (lysyl …
cancer metastasis is a major factor in the failure of CRC therapy. Recently, LOXL2 (lysyl …
Development of a TaqMan real-time PCR assay with an internal amplification control for detecting trace amounts of allergenic mango (Mangifera indica) in …
HY Yin, YF Liu, YY Lin, TC Kao, WC Tsai… - … Food Research and …, 2023 - Springer
Mango (Mangifera indica) is a widely enjoyed tropical fruit that is rich in numerous nutrients,
but it is also a common allergenic fruit that can induce anaphylactic shock in some mango …
but it is also a common allergenic fruit that can induce anaphylactic shock in some mango …
[HTML][HTML] MicroRNAs and other mechanisms regulate interleukin-17 cytokines and receptors
Interleukin-17 cytokines are a family of pro-inflammatory cytokines. Our current studies
found: i) IL-17 cytokines are not ubiquitously expressed, but several receptors and …
found: i) IL-17 cytokines are not ubiquitously expressed, but several receptors and …
Genome-wide in silico mapping of scaffold/matrix attachment regions in Arabidopsis suggests correlation of intragenic scaffold/matrix attachment regions with gene …
We carried out a genome-wide prediction of scaffold/matrix attachment regions (S/MARs) in
Arabidopsis. Results indicate no uneven distribution on the chromosomal level but a clear …
Arabidopsis. Results indicate no uneven distribution on the chromosomal level but a clear …
LOX and LOXL2 inhibitors and uses thereof
V Smith, S Ogg, P Van Vlasselaer, VE Barry… - US Patent …, 2013 - Google Patents
2008-11-03 Assigned to ARRESTO BIOSCIENCES, INC. reassignment ARRESTO
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Antibodies that bind to lysyl oxidase-like 2 (LOXL2)
SA McCauley, H Rodriguez, CA Garcia… - US Patent …, 2014 - Google Patents
The present disclosure provides lysyl oxidase-like-2 (LOXL2) polypeptide binding agents,
including, for example, antibodies that speci? cally bind a LOXL2 polypep tide; and further …
including, for example, antibodies that speci? cally bind a LOXL2 polypep tide; and further …