Antibiotic adjuvants: a versatile approach to combat antibiotic resistance

G Dhanda, Y Acharya, J Haldar - ACS omega, 2023 - ACS Publications
The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging
even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut …

Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

[PDF][PDF] Next-Generation strategies to combat antimicrobial resistance: Integrating genomics, CRISPR, and novel therapeutics for effective treatment

AO Olatunji, JA Olaboye, CC Maha… - … & Technology Journal, 2024 - researchgate.net
Olatunji, Olaboye, Maha, KOlawole, & Abdul, P. No. 2284-2303 Page 2285 therapy, and
synthetic biology-derived compounds, provides alternative treatment options. These …

Intrinsic antimicrobial resistance: molecular biomaterials to combat microbial biofilms and bacterial persisters

S Barman, LB Kurnaz, R Leighton, MW Hossain… - Biomaterials, 2024 - Elsevier
The escalating rise in antimicrobial resistance (AMR) coupled with a declining arsenal of
new antibiotics is imposing serious threats to global public health. A pervasive aspect of …

Polymeric biomaterials for prevention and therapeutic intervention of microbial infections

S Ghosh, S Mukherjee, D Patra, J Haldar - Biomacromolecules, 2022 - ACS Publications
The escalating emergence of multidrug-resistant (MDR) pathogens and their ability to
colonize into biofilms on a multitude of surfaces have struck global health as a nightmare …

Stimuli-Responsive Release-Active Dressing: A Promising Solution for Eradicating Biofilm-Mediated Wound Infections

R Dey, R Mukherjee, S Biswas… - ACS Applied Materials & …, 2024 - ACS Publications
Biofilm-mediated wound infections pose a significant challenge due to the limitations of
conventional antibiotics, which often exhibit narrow-spectrum activity, fail to eliminate …

Smart multifunctional polymer systems as alternatives or supplements of antibiotics to overcome bacterial resistance

D Pranantyo, K Zhang, Z Si, Z Hou… - …, 2022 - ACS Publications
In recent years, infectious diseases have again become a critical threat to global public
health largely due to the challenges posed by antimicrobial resistance. Conventional …

[HTML][HTML] Facial amphiphilicity index correlating chemical structures with antimicrobial efficacy

LB Kurnaz, Y Luo, X Yang, A Alabresm, R Leighton… - Bioactive Materials, 2023 - Elsevier
Facial amphiphilicity is an extraordinary chemical structure feature of a variety of
antimicrobial peptides and polymers. Vast efforts have been dedicated to small molecular …

Photo‐Crosslinked Antimicrobial Hydrogel Exhibiting Wound Healing Ability and Curing Infections In Vivo

R Dey, R Mukherjee, J Haldar - Advanced Healthcare …, 2022 - Wiley Online Library
With the increasing focus on healthcare research in the current times, therapeutic and
biomaterial interventions for healing of wounds and mitigation of wound‐associated …

Amphiphilic nano-swords for direct penetration and eradication of pathogenic bacterial biofilms

C Zhou, Y Zhou, Y Zheng, Y Yu, K Yang… - … Applied Materials & …, 2023 - ACS Publications
Bacterial biofilms are major causes of persistent and recurrent infections and implant
failures. Biofilms are formable by most clinically important pathogens worldwide, such as …