The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …

Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Nano medicine had viewed countless breakthroughs in drug delivery implementations. The
main objective of nanotechnology application in delivering and carrying many promising …

Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

Scope Exosomes, small vesicles participating in intercellular communication, have been
extensively studied recently; however, the role of edible plant derived exosomes in …

The emerging field of precision medicine is rapidly growing, fostered by the advances in
genome mapping and molecular diagnosis. In general, the translation of these advances …

The low-efficiency cellular uptake property of current nanoparticles greatly restricts their
application in the biomedical field. Herein, we demonstrate that novel virus-like mesoporous …

Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …

Oxidative stress, caused by excessive production of reactive oxygen species (ROS), plays a
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …