Insect trehalase: physiological significance and potential applications

E Shukla, LJ Thorat, BB Nath, SM Gaikwad - Glycobiology, 2015 - academic.oup.com
Trehalose, a non-reducing disaccharide, is widespread throughout the biological world. It is
the major blood sugar in insects playing a crucial role as an instant source of energy and in …

Glycosidase inhibition: assessing mimicry of the transition state

TM Gloster, GJ Davies - Organic & biomolecular chemistry, 2010 - pubs.rsc.org
Glycoside hydrolases, the enzymes responsible for hydrolysis of the glycosidic bond in di-,
oligo-and polysaccharides, and glycoconjugates, are ubiquitous in Nature and fundamental …

Biochemistry and molecular biology of digestion

WR Terra, C Ferreira - Insect molecular biology and biochemistry, 2012 - Elsevier
Publisher Summary The aim of this chapter is to review the recent and spectacular progress
in the study of insect digestive biochemistry. It tries to establish uniform parameters for …

Stereocontrolled cyclic nitrone cycloaddition strategy for the synthesis of pyrrolizidine and indolizidine alkaloids

A Brandi, F Cardona, S Cicchi… - … –A European Journal, 2009 - Wiley Online Library
The synthesis of polyhydroxylated indolizidines and pyrrolizidines belonging to the class of
iminosugars, endowed with a vast and assorted biological activity, can be achieved in a …

[图书][B] Carbohydrate chemistry and biochemistry: structure and mechanism

M Sinnott - 2013 - books.google.com
This graduate textbook is aimed at providing researchers new to the subject with information
on the structure and mechanisms in the chemistry, biochemistry or processing of …

Mechanistic insights into a Ca2+-dependent family of α-mannosidases in a human gut symbiont

Y Zhu, MDL Suits, AJ Thompson, S Chavan… - Nature chemical …, 2010 - nature.com
Colonic bacteria, exemplified by Bacteroides thetaiotaomicron, play a key role in
maintaining human health by harnessing large families of glycoside hydrolases (GHs) to …

Suppressing the activity of trehalase with validamycin disrupts the trehalose and chitin biosynthesis pathways in the rice brown planthopper, Nilaparvata lugens

B Tang, M Yang, Q Shen, Y Xu, H Wang… - Pesticide biochemistry …, 2017 - Elsevier
Trehalase (TRE) is a key enzyme in trehalose degradation and has important functions in
insect growth and chitin synthesis. Though validamycin has the potential for pest control by …

Molecular physiology of insect midgut

WR Terra, IG Barroso, RO Dias, C Ferreira - Advances in insect physiology, 2019 - Elsevier
New approaches have led to advances in the molecular knowledge of digestion and nutrient
absorption in insects. Cell fractionation with proteomics revealed the molecular composition …

[PDF][PDF] Mechanisms of the 14-3-3 protein function: regulation of protein function through conformational modulation.

V Obsilova, M Kopecka, D Kosek… - Physiological …, 2014 - pdfs.semanticscholar.org
Many aspects of protein function regulation require specific protein-protein interactions to
carry out the exact biochemical and cellular functions. The highly conserved members of the …

Tailoring trehalose for biomedical and biotechnological applications

MK O'Neill, BF Piligian, CD Olson… - Pure and Applied …, 2017 - degruyter.com
Trehalose is a non-reducing sugar whose ability to stabilize biomolecules has brought about
its widespread use in biological preservation applications. Trehalose is also an essential …