Chordoma—current understanding and modern treatment paradigms

SM Barber, SS Sadrameli, JJ Lee, JS Fridley… - Journal of clinical …, 2021 - mdpi.com
Chordoma is a low-grade notochordal tumor of the skull base, mobile spine and sacrum
which behaves malignantly and confers a poor prognosis despite indolent growth patterns …

[PDF][PDF] Ary

R JÚNIOR - Entrevista: Prof. Dr. Ary Rocco Junior [set. 2015] …, 2015 - scholar.archive.org
Supplementary Table S1. Search Terms Page 1 1 Supplementary Table S1. Search Terms
Pubmed: 442 results ("Chordoma"[Mesh] OR "chordoma"[tw] OR "chordomas"[tw] OR "chorda"[tw] …

The sacral chordoma margin

S Radaelli, P Fossati, S Stacchiotti, T Akiyama… - European Journal of …, 2020 - Elsevier
Objective Aim of the manuscript is to discuss how to improve margins in sacral chordoma.
Background Chordoma is a rare neoplasm, arising in half cases from the sacrum, with …

Apatinib in patients with advanced chordoma: a single-arm, single-centre, phase 2 study

C Liu, Q Jia, H Wei, X Yang, T Liu, J Zhao… - The Lancet …, 2020 - thelancet.com
Background No standard treatment exists for advanced chordoma. Apatinib has been found
to have promising efficacy and manageable adverse effects for the treatment of solid …

[HTML][HTML] Medical treatment of advanced chordomas

V Colia, S Stacchiotti - European Journal of Cancer, 2017 - Elsevier
Chordoma is a very rare bone sarcoma that can arise from any site along the spine and from
the skull base. En bloc resection is the gold standard for treatment while radiation therapy …

Chordomas of the skull base, mobile spine, and sacrum: an epidemiologic investigation of presentation, treatment, and survival

SL Zuckerman, MH Bilsky, I Laufer - World Neurosurgery, 2018 - Elsevier
Background Chordomas are rare primary bone tumors that arise from the axial skeleton. Our
objective was to analyze trends in radiation and surgery over time and determine location …

CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway

W Yuan, F Wei, H Ouyang, X Ren, J Hang, X Mo… - Cancer Cell …, 2021 - Springer
Background Chordomas are rare, slow-growing and locally aggressive bone sarcomas. At
present, chordomas are difficult to manage due to their high recurrence rate, metastasis …

The relationship between tumor-stroma ratio, the immune microenvironment, and survival in patients with spinal chordoma

MX Zou, BW Zheng, FS Liu, XB Wang, JR Hu… - …, 2019 - journals.lww.com
BACKGROUND Currently, little is known about the clinical relevance of tumor-stroma ratio
(TSR) in chordoma and data discussing the relationship between TSR and immune status of …

Chordoma of the sacrum and mobile spine: a narrative review

Z Pennington, J Ehresman, EF McCarthy, AK Ahmed… - The Spine Journal, 2021 - Elsevier
Chordoma is a notochord-derived primary tumor of the skull base and vertebral column
known to affect 0.08 to 0.5 per 100,000 persons worldwide. Patients commonly present with …

[HTML][HTML] Gross total resection and survival outcomes in elderly patients with spinal chordoma: a SEER-based analysis

J Pham, E Shaaya, B Rhee, A Kimata, EE Ozcan… - Frontiers in …, 2024 - frontiersin.org
Objective The association between aggressive resection and improved survival for adult
spinal chordoma patients has not been well characterized in the geriatric population. Thus …