Combatting the evolution of antifungal resistance in Cryptococcus neoformans
A Bermas, J Geddes‐McAlister - Molecular microbiology, 2020 - Wiley Online Library
Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
Cryptococcal Disease in Diverse Hosts
DB Meya, PR Williamson - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …
Single-dose liposomal amphotericin B treatment for cryptococcal meningitis
Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …
Antifungal combinations for treatment of cryptococcal meningitis in Africa
SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …
Recent trends in the epidemiology of fungal infections
EE Seagle, SL Williams, TM Chiller - Infectious Disease Clinics, 2021 - id.theclinics.com
Discussion The epidemiology of fungal diseases is constantly evolving. Environmental
changes, medical advancements, emerging species, and diagnostic and therapeutic …
changes, medical advancements, emerging species, and diagnostic and therapeutic …
Global HIV neurology: a comprehensive review
Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …
mortality and are increasingly recognized in the aging population on long-standing …
Cryptococcal meningoencephalitis: time for action
Cryptococcal meningoencephalitis was first described over a century ago. This fungal
infection is preventable and treatable yet continues to be associated with excessive …
infection is preventable and treatable yet continues to be associated with excessive …
Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries
A Loyse, J Burry, J Cohn, N Ford, T Chiller… - The Lancet Infectious …, 2019 - thelancet.com
In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-
related cryptococcal disease. Two strategies are recommended to reduce the high mortality …
related cryptococcal disease. Two strategies are recommended to reduce the high mortality …
The changing epidemiology of HIV-associated adult meningitis, Uganda 2015–2017
J Ellis, AS Bangdiwala, FV Cresswell… - Open forum …, 2019 - academic.oup.com
Background Central nervous system (CNS) infections remain a major public health problem
in Sub-Saharan Africa, causing 15%–25% of AIDS-related deaths. With widespread …
in Sub-Saharan Africa, causing 15%–25% of AIDS-related deaths. With widespread …
How applicable is the single-dose ambition regimen for human immunodeficiency virus–associated cryptococcal meningitis to high-income settings?
TS Harrison, DS Lawrence… - Clinical Infectious …, 2023 - academic.oup.com
Abstract The AmBisome Therapy Induction Optimization (AMBITION-cm) trial, conducted in
eastern and southern Africa, showed that a single, high dose (10 mg/kg) of liposomal …
eastern and southern Africa, showed that a single, high dose (10 mg/kg) of liposomal …